Publikationen

2024

Peer reviewed articles

Zangenehzadeh, S., Agocs, E., Schröder, F., Amroun, N., Biedendieck, R., Jahn, D., Günther, A., Zheng, L., Roth, B., Johannes, H.-H. & Kowalsky, W. (2024)
Polarization modulated spectroscopic ellipsometry-based surface plasmon resonance biosensor for E. coli K12 detection.
Sci Rep. in press.

DOI: 10.1016/j.procir.2024.08.204
Zimbelmann, S., Hintmann, M., Baumann, M., Jahn, D., Biedendieck, R. & Emde, B. (2024)
Selective Lethal Impact of Blue Laser Radiation Compared to High-Power LED Irradiation on Naturally Grown Biofouling in the Context of Underwater Biofouling Cleaning.
Procedia CIRP. 124, 696–699

PUBMED: 39206375
Piskol, F., Lukat, P., Kaufhold, L., Heger, A., Blankenfeldt, W., Jahn, D.  & Moser, J. (2024)
Biochemical and structural elucidation of the L-carnitine degradation pathway of the human pathogen Acinetobacter baumannii
Front Microbiol. 15, 1446595

DOI: 10.3390/ijms25136905
Muñoz-Villagrán, C., Acevedo-Arbunic, J., Härtig, E., Sievers, S., Zühlke, D., Issotta, F., Mascayano, C., Jahn, D., Jahn, M., & Levicán, G. (2024)
The thioredoxin fold protein (TFP2) from extreme acidophilic Leptospirillum sp. CF-1 is a chaperedoxin-like protein that pre-vents the aggregation of proteins under oxidative stress
Int J Mol Sci. (IJMS), 25, 6905

PUBMED: 38544863
Mingers, T., Mass, V., Barthels, S., Borrero De Acuña, S.M., Biedendieck, R., Cooke, A., Dailey, T., Gerdes, S., Blankenfeld, W., Dailey, H., Warren, M., Jahn, M. & Jahn, D. (2024)
The Alternative Coproporphyrinogen III Oxidase (CgoN) Catalyzes the Oxygen-independent Conversion of Coproporphyrinogen III into Coproporphyrin III
Front Microbiol. 15, 1378989

DOI: 10.3390/photonics11030220
Hintmann, M., Zimbelmann, S., Emde, B., Biedendieck, R. & Jahn, D. (2024)
Antibiotic Effect of High-Power Blue Laser Radiation
Photonics 11, 220

PUBMED: 38404597
Pucelik, S., Becker, M., Heyber, S., Wöhlbrand, L., Rabus, R. A., Jahn, D. & Haertig, E. (2024)
The blue light-dependent LOV-protein LdaP of Dinoroseobacter shibae acts as antirepressor of the PpsR repressor, regulating photosynthetic gene cluster expression
Front Microbiol, 15, 1351297

Book articles and Reviews

Simon, M., Brinkhoff, T., Cypionka, H., Dittmar, T., Engelen, B., Blasius, B., Niggemann, J., Rabus, R., Moraru, C., Daniel, R., Jahn, D., Wagner-Doebler, I., Härtig, E., Schulz, S., Schomburg, D., Hiller, K., Göker, M., Overmann, J., Petersen, J., Pradella, S. & Dickschat, J. (2024)
Transregional Collaborative Research Centre (TRR 51) Ecology, Physiology and Molecular Biology of the Roseobacter Group: Towards a Systems Biology Understanding of a Globally Important Group of Marine Bacteria. Zenodo. https://doi.org/10.5281/zenodo.13767435

DOI: 10.1007/978-3-031-63164-1_1
Wichmann, J., Staar, M., Kubiak, M., Solarczek, J., Mayer, J., Jahn, D., Kampen, I., Schilde, C., Schallmey, A. & Biedendieck, R. (2024)
Correlation of structure and properties of enzyme crystals in consideration of downstream processing and formulation.
In "Dispersity, Structure and Phase Changes of Proteins and Bio Agglomerates in Biotechnological Processes", Kwade, A. and Kampen, I. (Eds.) Springer Nature, S. 1-57

DOI: 10.1007/978-3-031-63164-1_6
Brune, S.E., Jahn, D., Krull, R. & Biedendieck, R. (2024)
Production, purification, and characterization of recombinant β-lactoglobulin variants.
In "Dispersity, Structure and Phase Changes of Proteins and Bio Agglomerates in Biotechnological Processes", Kwade, A. and Kampen, I. (Eds.) Springer Nature, S. 181-200

2023

Peer reviewed articles

PUBMED: 38067103
Kretschmer, M., Müller, J., Henke, P., Otto, V., Rodriguez, A.A., Müsken, M., Jahn, D., Borrero-de Acuña, J.M., Neumann-Schaal, M. & Wegner, A. (2023)
Isolation and Quantification of Bacterial Membrane Vesicles for Quantitative Metabolic Studies Using Mammalian Cell Cultures.
Cells 12: 2674

PUBMED: 37996937
Dougan, K.E., Zhi-Luo Deng, Z.-L., Wöhlbrand, L., Reuse, C., Bunk, B.,  Chen, Y., Hartlich, J., Hiller; K., John, U., Kalvelage, J., Mansky, J., Neumann-Schaal, M., Overmann, J., Petersen, J., Sanchez Garcia, S., Schmidt-Hohagen, K., Sha, S., Spröer, C., Sztajer, H., Wang, H., Bhattacharya, D., Rabus, R., Jahn, D., Xin Chan, C. & Wagner-Döbler, I. (2023)
Multi-omics analysis reveals the molecular response to heat stress in a “red tide” dinoflagellate
Genome Biology, 24: 265

PUBMED: 36596691
Hamed, M.M., Abdelsamie, A. S., Rox, K., Schütz, C., Kany, A. M., Röhrig, T., Schmelz, S., Blankenfeldt,W., Arce-Rodriguez, A., Borrero-de Acuña, J. M., Jahn, D., Rademacher, J., Ringshausen, F., Cramer, N., Tümmler, B., Hirsch, A. K. H.,  Hartmann R. W. & Empting, M. (2023)
Towards translation of PqsR inverse agonists: from in vitro efficacy optimization to in vivo proof-of-principle
Adv Sci., 10: e2204443

DOI: 10.1016/j.tsf.2022.139583
Zangenehzadeh, S., Agocs, E., Jivani, H., Könemund, L., Neumann, L., Hirschberg, F., Herdan, S., Biedendieck, R., Jahn, D., Roth, B.W., Johannes, H.-H. & Kowalsky, W. (2023)
Bacteria detection in a Kretschmann geometry flow cell at a plasmon-enhanced interface with spectroscopic ellipsometer.
Thin Solid Films., 764: 139583

Book articles and Reviews

Dudek, C. A., Overmann, J. & Jahn, D. (2023)
Vorhersage bakterieller Genregulation
BIOspektrum 19:252-254

2022

Peer reviewed articles

PUBMED: 36342970
Mangan, M.S.J., Gorki, F., Krause, K., Heinz, A., Pankow, A., Ebert,T., Jahn, .D, Hiller, K., Hornung, V., Maurer, M., Schmidt, F.I., Gerhard, R., Latz, E. (2022)
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
PLOS Biol. 20(11):e300135

PUBMED: 36066069
Piskol, F., Neubauer, K., Eggers, M., Bode, L. M., Jasper, J., Slusarenko, A., Reijerse, E., Lubitz, W., Jahn, D. & Moser, J. (2022)
Two-component carnitine monooxygenase from Escherichia coli: Functional characterization, Inhibition and mutagenesis of the molecular interface.
Biosc Rep., 42:BSR20221102

PUBMED:  35746797
Ballmann, R., Hotop, S.-K.,  Bertoglio, F., Steinke, S., Heine, P. A., Chaudhry, M.-Z., Jahn, D., Pucker, B., Baldanti, F., Piralla, A., Schubert,M., Čičin-Šain,L., Hust, M. & Dübel, S. (2022)
ORFeome phage display reveals a major immunogenic epitope on the S2 subdomain of SARS-CoV-2 Spike protein.
Viruses, 14:1326

PUBMED: 35783419
Biwer, P., Neumann-Schaal, M., Henke, P., Jahn, D. & Schulz, S. (2022)
Thiol metabolism and volatile metabolome of Clostridioides difficile.
Front Microbiol.,13:864587

PUBMED: 35292706
Könemund, L., Neumann, L., Hirschberg, F., Biedendieck, R., Jahn, D., Johannes, H.-H. & Kowalsky, W. (2022)
Functionalization of an Extended-Gate Field-Effect Transistor (EGFET) for Bacteria Detection.
Sci. Rep., 12:4397

PUBMED: 35106888
Michel, A.-M., Manuel Borrero-de Acuña, J. M., Molinari, G., Ünal, C. M., Will, S., Derksen, E., Barthels, S., Bartram, W., Schrader, M., Rohde, M., Zhang, H., Hoffmann, T., Neumann-Schaal, M., Bremer, E. & Jahn, D. (2022)
Cellular adaptation of Clostridioides difficile to high salinity encompasses a compatible solute-responsive change in cell morphology.
Env Microbiol., 24:1499-1517

PUBMED: 35154034
Mansky, J., Wang, H.,  Ebert, M., Tomasch, J., Härtig, E., Jahn, D. & Wagner-Döbler, I (2022)
The influence of genes on the “killer plasmid” of Dinoroseobacter shibae on its symbiosis with the dinoflagellate Prorocentrum minimum.
Front Microbiol., 12:804767.

PUBMED: 34850133
Dudek, C.-A. & Jahn, D. (2022)
PRODORIC: state-of-the-art database of prokaryotic gene regulation.
Nucleic Acids Res., 50(D1):D295-D302

Book articles and Reviews

PUBMED: 35464954
Neumann-Schaal, M., Groß, U., Just, I., & Jahn, D. (2022)
Editorial: The Deadly Secrets of C. difficile—Insights Into Host-Pathogen Interaction.
Front. Microbiol. 13:897612.

PUBMED: 35464962
Neumann-Schaal, M., Groß, U., Just, I., & Jahn, D. (2022)
Editorial: The Deadly Secrets of C. difficile—Insights Into Host-Pathogen Interaction Volume II.
Front. Microbiol. 13:896979.

PUBMED: 37101575
Layer, G., Jahn, M., Moser, J. & Jahn, D. (2022)
Radical SAM Enzymes Involved in Tetrapyrrole Biosynthesis and Insertion.
ACS Bio & Med Chem Au. 2:196-204

2021

Peer reviewed articles

PUBMED: 34177868
Brauer, M., Lassek, C., Hinze, C., Hoyer, J.,  Becher, D.,  Jahn, D., Sievers, S., & Riedel, K. (2021)
What’s a biofilm? – How the choice of the biofilm model impacts the protein inventory of Clostridioides difficile.
Front Microbiol., 12, 682111

PUBMED: 33780465
Beier, N, Kucklick, M, Fuchs, S., Mustafayeva, S., Behringer, M.,Härtig, E., Jahn, D., & Engelmann, S. (2021)
Adaptation of Dinoroseobacter shibae to oxidative stress and the specific role of RirA,
PLOS ONE, 16, e0248865

PUBMED: 33658275
Troitzsch, D., Zhang, H., Dittmann, S., Düsterhöft, D., Möller, T., Michel, A.-M., Jänsch, L., Riedel, K., Borrero-de Acuña, J., Jahn, D., & Sievers, S. (2021) 
A point mutation in the transcriptional repressor PerR results in a constitutive oxidative stress response in Clostridioides difficile 630Δerm,
mSphere, 6 e00091-21

PUBMED: 33610128
He, W., Heinz, A., Jahn, D., & Hiller, K. (2021)
Complexity of macrophage metabolism during infection,
Curr Opin Biotechnol., 68, 231-239

PUBMED: 33411772
Hofmann, J. D., Biedendieck, R.,  Michel, A. M., Schomburg, D.,  Jahn, D. &  Neumann-Schaal, M. (2021)
Influence of L-lactate and low glucose concentrations on the metabolism and the toxin formation of Clostridioides difficile,
PLOS ONE, 16, e0244988

DOI: https://doi.org/10.1016/j.foodhyd.2020.106132
Keppler, J., Heyse, A., Scheidler, E., Uttinger, M., Fitzner, L., Jandt, U., Heyn, T.R., Lautenbach, V., Loch, J., Lohr, J., Kieserling, H., Günther, G., Kempf, E., Grosch, J.-H., Lübbert, C., Lewinski, K., Jahn, D., Peukert, W., Kulozik, U., Drusch, S., Krull, R., Schwarz, K. & Biedendieck, R. (2021)
Towards recombinantly produced milk proteins: Physicochemical and emulsifying properties of engineered whey protein beta-lactoglobulin variants
Food Hydrocoll. 110, 106132

Book articles and Reviews

PUBMED: 34263356
Biedendieck, R., Knuuti, T., Moore, S. & Jahn, D. (2021)
The “Beauty in the beast” – the multiple uses of Priestia megaterium in biotechnology
Appl Microbiol Biotechnol. 105, 5719-5737

LINK: https://doi.org/10.1016/B978-0-12-819460-7.00328-5
Jahn, M., Jahn, D., and Warren, M.J. (2021)
Bioenergetics Theory and Components| Heme Synthesis Three Ways in: Encyclopedia of Biological Chemistry
3rd Ed. (Jez, J., Ed.), Elsevier
 

2020

Peer reviewed articles

PUBMED: 33211085
Wiesselmann, M., Hebecker, S., Borrero-de Acuña, J., Nimtz, M., Bollivar, D., Jänsch, L., Moser, J., & Jahn, D. (2021)
Mg-protoporphyrin IX monomethyl ester cyclase from Rhodobacter capsulatus: Radical SAM-dependent synthesis of the isocyclic ring of bacteriochlorophylls
Biochem. J., 477:4635-4654

PUBMED: 33211880
Chang, A., Jeske, L., Ulbrich, S., Hofmann, J., Koblitz, J., Schomburg, I., Neumann-Schaal, M., Jahn, D. & Schomburg, D. (2020)
BRENDA, the ELIXIR Core Data Resource in 2021: New Developments and Update.
Nucleic Acids Res., 49:D498-D508

PUBMED: 32938698
Boekhoud, I., Michel, A.-M., Corver, J., Jahn, D. &  Smits, W. K. (2020)
Redefining the Clostridioides difficile σ^B regulon: σ^B activates genes involved in detoxifying radicals that can result from the exposure to antimicrobials and hydrogen peroxide.
mSphere, 5:e00728-20

PUBMED: 32694223
Massmig, M., Reijerse, E., Krausze, J.,  Laurich, C.,  Lubitz, W., Jahn, D. & Moser, J. (2020)
Carnitine metabolism in the human gut: Characterization of the two-component carnitine monooxygenase CntAB from Acinetobacter baumannii
J. Biol. Chem., 295,13065-13078

PUBMED: 32290188
Zwaag, J., ter Horst, R., Blaženović, I., Stoessel, D., Ratter, J., Worseck, J., Schauer, N., Stienstra, R., Netea, M., Jahn, D., Pickkers, P. & Kox, M. (2020)
Involvement of lactate and pyruvate in the anti-inflammatory effects exerted by voluntary activation of the sympathetic nervous system
Metabolites 10,E148

DOI: /10.1002/celc.202000027
Kubannek, F., Thiel, S., Bunk, B., Huber, K., Overmann, J., Krewer, U., Biedendieck, R. & Jahn, D. (2020)
Performance modelling of the bioelectrochemical glycerol oxidation by a co-culture of Geobacter sulfurreducens and Raoultella electrica
ChemElectroChem. 7,1877-1888

PUBMED: 31958206
Jasper, J., Vazquez Ramos, J., Trncik, C., Jahn, D., Einsle, O., Layer, G. & Moser, J. (2020)
Chimeric Interaction of Nitrogenase-like Reductases with the MoFe Protein of Nitrogenase.
ChemBioChem., 21,1733-1741

PUBMED: 31860023
Behringer, M., Plötzky, L., Baabe, D., Zaretzke, M.-K., Schweyen, P., Bröring, M., Jahn, D., & Härtig, E. (2020)
RirA of Dinoroseobacter shibae senses iron via a [3Fe-4S]1+ cluster coordinated by three cysteine residues.
Biochem. J., 477,191-212

Book articles and Reviews

Jahn, M., Jahn, D., Moran, L. A., Horton, H. R., Scrimgeour, R. G., & Perr, M. D. (2020)
Horton Biochemie kompakt.
Pearson Studium, Pearson Deutschland, Munich, Germany

2019

Peer reviewed articles

Jaensch, L.,  Bernal, I., Scheibel,J., Groebe, L.,  Klawonn,F.,  Neumann-Schaal, M.,  Hofmann, J.D.,  Michel, A.M., Jahn, D.,  Gerhard, R. &  Bruder, D. (2019) 
Role of human mucosal-associated invariant T (MALT) cells in age-associated Clostridium difficile infections.
Europ. J. Immun. 49, 143-144.

PUBMED: 31649093
Thiel, S., Bunk, B., Spröer, C., Overmann, J., Jahn, D. & Biedendieck, R. (2019)
Complete genome sequence of Raoultella electrica 1GB (DSM 102253T), isolated from anodic biofilms of a glucose-fed microbial fuel cell.
Microbiol Resour Announc 8(43)

PUBMED: 31227867
Mayer, J., Pippel, J., Günther, G., Müller, C., Lauermann, A., Knuuti, T., Blankenfeldt, W., Jahn, D. & Biedendieck, R. (2019)
Crystal structures and protein engineering of three different penicillin G acylases from Gram-positive bacteria with different thermostability.
Appl Microbiol Biotechnol. 103:7537-7552

PUBMED: 30912268
Timmis, K.N., Cavicchioli, R., Garcia, J.L., Nogales, B., Chavarría, M., Stein, L., McGenity, T.J., Webster, N., Singh, B., Handelsman, J., de Lorenzo, V., Pruzzo, C., Timmis, J., Ramos Martín, J.L., Verstraete, W., Jetten, M., Danchin, A., Huang, W., Gilbert, J., Lal, R., Santos, H., Sang, S.Y., Sessitsch, A., Bonfante, P., Gram, L., Lin, R.T.P., Ron, E., Karahan, C., van der Meer, J.R., Artunkal, S., Jahn, D. & Harper, L. (2019)
The urgent need for microbiology literacy in society
Environ. Microbiol. 21:1513-1528

PUBMED: PMC6459899
Ünal, C. M., Karagöz, M. S., Berges, M., Priebe, C., Borrero De Acuña, J. M., Wissing, J., Jänsch, L., Jahn, D. & Steinert, M. (2019)
Pleiotropic Clostridioides difficile cyclophilin PpiB controls cysteine-tolerance, toxin production, the central metabolism and multiple stress responses
Front. Pharmacol. 10:340

PUBMED: 30835726
Münch, K., Münch, R., Biedendieck, R., Jahn, D. & Müller, J. (2019)
Evolutionary model for the unequal segregation of high copy plasmids
PLOS Comp. Biol., 15:e1006724

PUBMED: 30608141
Blaženović, I., Kind, T., Sa, M., Ji, J., Vaniya, A., Wancewicz, B., Roberts, B., Torbasinovic, H., Lee, T., Mehta, S., Showalter, M., Song, H., Kwok, J., Jahn, D., Kim, J. & Fiehn, O. (2019)
Structure annotation of all mass spectra in untargeted metabolomics
Anal. Chem., 91:2155-2162

PUBMED: 30353924
Groenewald, M., Hebecker, S., Fritz, C., Czolkoss, S., Wieselmann, M., Heinz, D., Jahn, D., Narberhaus, F., Meriyem, A. & Moser, J. (2019)
Virulence of Agrobacterium tumefaciens requires Lipid Homeostasis mediated by the Lysyl-Phosphatidylglycerol Hydrolase
Mol. Microbiol., 111:269-286

Book articles and Reviews

Jahn, D. & Timmis, K. (2019)
Mikrobiologisches Wissen für alle bedeutet Klimaschutz!
BIOspektrum 25: 595.

PUBMED: 30828322
Neumann-Schaal, M., Jahn, D. & Schmidt-Hohagen, K. (2019)
Metabolism the difficile way - the key to the success of the pathogen Clostridioides difficile
Front. Microbiol., 10:219

Müller, K., Mingers,  T., Haskamp, V., Jahn, D.  & Jahn, M (2019)
Biosynthesis and Insertion of Heme
in "Handbook of Hydrocarbon and Lipid Microbiology Series. Aerobic Utilization of Hydrocarbons, Oils, and Lipids", Rojo, F. (Eds.) Springer Nature, Cham, Schweiz, 201 – 228

2018

PUBMED: 30619231
Berges, M. ,  Michel, A.-M., Lassek, C., , Nuss, A. M., Beckstette, M., Dersch, P., Riedel, K., Sievers, S., Becher, D., Otto, A. ,  Maaß, S., Rohde, M., Eckweiler, D., Borrero-de Acuna, J. M., Jahn, M. J., Neumann-Schaal, M. & Jahn, D. (2018)
Iron regulation in Clostridioides difficile
Front. Microbiol., 9:3183

PUBMED: 30564207
Ünal, C. M., Berges, M., Smit,N. Schiene-Fischer, C., Priebe, C., Strowig, T., Jahn, D. & Steinert, M. (2018)
PrsA2 (CD630_35000) of Clostridioides difficile is an active parvulin-type PPIase and a virulence modulator
Front. Microbiol., 9:2913

PUBMED: 30410474
Bernal, I, Hofmann, J. D., Bulitta, B., Klawonn, F., Michel, A.-M., Jahn, D., Neumann-Schaal, M., Bruder, D. & Jänsch, L. (2018)
Clostridioides difficile activates human mucosal-associated invariant T cells.
Front. Microbiol., 9:2532

PUBMED: 30186274
Hofmann, J. D., Otto, A., Berges, M., Biedendieck, R., Michel, A.-M., Becher, D., Jahn, D. & Neumann-Schaal, M. (2018)
Metabolic reprogramming of Clostridioides difficile during the stationary phase with the induction of toxin production.
Front. Microbiol., 9:1970

PUBMED: 30039521
Härtig, E., Frädrich, C., Behringer, M., Hartmann, A. , Neumann-Schaal, M. & Jahn, D. (2018)
Functional definition of the two effector binding sites, the oligomerization and DNA binding domains of the Bacillus subtilis LysR-type transcriptional regulator AlsR.
Mol. Microbiol., 109:845-864

PUBMED: 29717024
Groenewold, M., Massmig, M., Hebecker, S., Danne, L., Magnowska, Z., Nimtz, M., Narberhaus, F., Jahn, D., Heinz, D.W., Jänsch, L. & Moser, J. (2018)
A phosphatidic acid binding protein is important for lipid homeostasis and adaptation to anaerobic biofilm conditions in Pseudomonas aeruginosa.
Biochem J. 475:1885–1907

PUBMED: 29867814
Kirchhoff, C., Ebert, M., Jahn, D. & Cypionka, H. (2018)
Chemiosmotic energy conservation in Dinoroseobacter shibae: Proton translocation driven by aerobic respiration, denitrification and photosynthetic light reaction.
Front. Microbiol. 9:903

PUBMED: 29282292
Haskamp, V., Karrie, S., Mingers, T., Barthels, S., Alberge, F., Magalon, A., Müller, K., Bill, E., Lubitz, W., Kleeberg, K., Schweyen, P., Bröring, M., Jahn, M. & Jahn, D. (2018)
The radical SAM protein HemW is a heme chaperone.
J Biol Chem. 293:2558-2572

2017

Peer reviewed articles

PUBMED: 29136200
Eckweiler, D., Dudek, C.-A., Hartlich, J., Broetje, D. & Jahn, D. (2017)
PRODORIC2: the bacterial gene regulation database in 2018.
Nucleic Acids Res. 46:D320-D326

PUBMED: 28857512
Borrero-de Acuña, J.M., Timmis, K.N., Jahn, M. & Jahn, D. (2017)
Protein complex formation during denitrification by Pseudomonas aeruginosa.
Microb Biotechnol. 10:1523-1534

PUBMED: 28765283
Ebert, M., Schweyen, P., Bröring, M., Laass, S., Härtig, E. & Jahn, D. (2017)
Heme and nitric oxide binding by the transcriptional regulator DnrF from the marine bacterium Dinoroseobacter shibae increases napD promoter affinity.
J. Biol. Chem. 292:15468-15480

PUBMED: 28619474
Riedel, T., Wetzel, D., Hofmann, J.D., Plorin, S.P.E.O., Dannheim, H., Berges, M., Zimmermann, O., Bunk, B., Schober, I., Spröer, C., Liesegang, H., Jahn, D., Overmann, J., Groß, U. & Neumann-Schaal, M. (2017)
High metabolic versatility of different toxigenic and non-toxigenic Clostridioides difficile isolates
Int. J. Med. Microbiol. 307:311-320

PUBMED: 29086039
Blaženović, I., Kind, T., Torbašinović, H., Obrenović, S., Mehta, S.S., Tsugawa, H., Wermuth, T., Schauer, N., Jahn, M., Biedendieck, R., Jahn, D. & Fiehn, O. (2017)
Comprehensive comparison of in silico MS/MS fragmentation tools of the CASMI contest: database boosting is needed to achieve 93% accuracy
J. Cheminform. 9:32

PUBMED: 28473807
Ebert, M., Laass, S., Thürmer, A., Roselius L., Eckweiler, D., Daniel, R., Härtig, E. & Jahn, D. (2017)
FnrL and three Dnr regulators are used for the metabolic adaptation to low oxygen tension in Dinoroseobacter shibae.
Front. Microbiol. 8:642

Books, Book articles and Reviews

Jahn, D. (2017)
Das Mikrobiom. Dein Freund und Helfer
Audi BKK Magazin-Gesundheit 02/2017, Seite 8-13

PUBMED: 28123057
Dailey, H., Dailey, T., Gerdes, S., Jahn, D., Jahn, M., O´Brian, M. & Warren, M. J. (2017)
Prokaryotic heme biosynthesis: mutiple pathways to a common essential product.
Microbiol. Mol. Biol. Rev. 81:e00048-16

2016

Peer reviewed articles

PUBMED: 28006011
Nuss, A. M., Schuster, F., Roselius L., Klein, J., Bücker, R., Herbst, K., Heroven, A. K., Pisano, F., Wittmann, C., Münch, R., Müller, J., Jahn, D. & Dersch, P. (2016)
A precise temperature-responsive bistable switch controlling Yersinia virulence.
PLOS Pathogens, 12: e1006091

PUBMED: 27466367
Füller, J. J., Röpke, R., Krausze, J., Rennhack, K. E., Daniel, N. P., Blankenfeldt, W., Schulz, S., Jahn, D. & Moser J. (2016)
Biosynthesis of Violacein: Structure and Function of L-Tryptophan Oxidase VioA from Chromobacterium violaceum.
J. Biol. Chem., 291: 20068-20084

PUBMED: 27303368
Patzelt, D., Michael, V., Päuker, O., Ebert, M., Tielen, P., Jahn, D., Tomasch, J., Petersen, J. & Wagner-Döbler, I. (2016)
Gene flow across genus barriers - Conjugation of Dinoroseobacter shibae's 191-kb killer plasmid into Phaeobacter inhibens and AHL-mediated expression of type IV secretion systems.
Front. Microbiol., 7: 742

PUBMED: 26903416
Borrero-de Acuna, J. M., Rohde, M., Wissing, J., Jänsch, L., Schobert, M., Molinari, G., Timmis, K. N., Jahn, M. & Jahn, D. (2016)
Protein Network of the Pseudomonas aeruginosa Denitrification Apparatus
J. Bacteriol., 198: 1401-1413

PUBMED: 26853478
Ferrer, A., Bunk, B., Spröer, C., Biedendieck, R., Valdés, N., Jahn, M., Jahn, D., Orellana, O. & Levican, G. (2016)
Complete genome sequence of the bioleaching bacterium Leptospirillum sp. group II strain CF-1.
J. Biotechnol., 222: 21-22.

Books, Book articles and Reviews

Rabus, R., Engelmann, S., Jahn, D., Petersen, J., Schomburg, D., Schulz, S. & Wagner-Döbler, I. (2016)
Systembiologie der marinen Roseobacter-Gruppe
Systembiologie, 11: 16-19

2015

Peer reviewed articles

PUBMED: 26261323
Hebecker, S. , Krausze, J., Hasenkampf, T., Schneider, J., Groenewold, M., Reichelt, J., Jahn, D., Heinz, D. W. & Moser, J. (2015)
Structures of two bacterial resistance factors mediating tRNA-dependent aminoacylation of phosphatidylglycerol with lysine or alanine
Proc. Natl. Acad. Sci. USA, 112:10691-10696

PUBMED: 26170416
Borrero-de Acuña, J. M., Molinari, G., Rohde, M., Dammeyer, T., Wissing, J., Jänsch, L., Arias, S. , Jahn, M. , Schobert, M. , Timmis, K.N. & Jahn, D. (2015)
A periplasmic complex of the nitrite reductase NirS, the chaperone DnaK and the flagellum protein FliC is essential for flagellum assembly and motility in Pseudomonas aeruginosa
J Bacteriol., 197:3066-3075

PUBMED: 26216844
Rücker, N., Billig, S., Bücker, R., Jahn, D., Wittmann, C. & Bange F. C. (2015)
Acetate dissimilation and assimilation in Mycobacterium tuberculosis depend on carbon availability
J Bacteriol., 197:3182-3190

PUBMED: 26088139
Lange, C., Kiesel, S., Peters, S., Virus, S., Scheer, H., Jahn, D. & Moser, J. (2015)
Broadened Substrate Specificity of 3-Hydroxyethyl Bacteriochlorophyllide α Dehydrogenase (BchC) Indicates a New Route for the Biosynthesis of Bacteriochlorophyll α
J Biol Chem., 290:19697-19709

PUBMED: 26116677
Münch, K., Müller, J., Wienecke, S., Bergmann, S., Heyber, S., Biedendieck, R., Münch, R. & Jahn, D. (2015)
Polar fixation of plasmids during recombinant protein production in Bacillus megaterium results in population heterogeneity.
Appl Environ Microbiol., 81:5976-5986

PUBMED: 26184943
Wibberg, D., Tielen, P., Narten, M., Schobert, M., Blom, J., Schatschneider, S., Meyer, A.-K., Neubauer, R., Albersmeier, A., Albaum, S., Jahn, M., Goesmann, A., Vorhölter, F.-J., Pühler, A. & Jahn, D. (2015)
Genome sequence of the urethral isolate Pseudomonas aeruginosa RN21
GenomeA, 3: e00788-15

PUBMED: 25776700
Zischka, M., Künne, C.T., Blom, J., Wobser, D., Sakιnç, T., Schmidt-Hohagen, K., Dabrowski, P.W., Nitsche, A., Hübner, J., Hain, T., Chakraborty, T., Linke, B., Goesmann, A., Voget, S., Daniel, R., Schomburg, D., Hauck, R., Hafez, H.M., Tielen, P., Jahn, D., Solheim, M., Sadowy, E., Larsen, J., Jensen, L.B., Ruiz-Garbajosa, P., Quiñones Pérez, D., Mikalsen, T., Bender, J., Steglich, M., Nübel, U., Witte, W. & Werner, G. (2015)
Comprehensive molecular, genomic and phenotypic analysis of a major clone of Enterococcus faecalis MLST ST40
BMC Genomics. 16:1367

PUBMED: 25673765
Lassek, C., Burghartz, M., Chaves-Moreno, D., Otto, A., Hentschker, C., Fuchs, S., Bernhardt, J., Jauregui, R., Neubauer, R., Becher, D., Pieper, D.H., Jahn, M., Jahn, D. & Riedel, K. (2015)
A Metaproteomics approach to elucidate host and pathogen protein expression during catheter-associated urinary tract infections
Mol Cell Proteomics, 14:989-1008

PUBMED: 25767242
Vorhölter, F.-J., Tielen, P., Wibberg, D., Narten, M., Schobert, M., Tüpker, R., Blom, J., Schatschneider, S., Winkler, A., Albersmeier, A., Goesmann, A., Pühler, A. & Jahn, D. (2015)
Genome Sequence of the Urethral Catheter Isolate Pseudomonas aeruginosa MH19
GenomeA, 3: e00115-15

PUBMED: 25616803
Klingner, A., Bartsch, A., Dogs, M., Wagner-Döbler, I., Jahn, D., Simon, M., Brinkhoff, T., Becker, J. & Wittmann, C. (2015)
Large-scale 13C-flux profiling reveals conservation of the Entner-Doudoroff pathway as glycolytic strategy among glucose-using marine bacteria
Appl Environ Microbiol., 81:2408-2422

PUBMED: 25422320
Kiesel, S., Wätzlich, D., Lange, C., Reijerse, E., Bröcker, M.J., Rüdiger, W., Lubitz, W., Scheer, H., Moser, J. & Jahn, D. (2015)
Iron-sulfur cluster-dependent catalysis of chlorophyllide a oxidoreductase from Roseobacter denitrificans
J Biol Chem., 290:1141-1154

Books, Book articles and Reviews

Borrero-de Acuña, J.M., Jänsch, L., Rohde, M., Timmis, K.N., Jahn, D. & Jahn, M. (2015)
Interatomic characterization of protein-protein interactions in membrane associated mega-complexes
in Hydrocarbon and Lipid Microbiology Protocols, ed. Kenneth Timmis; in press

Jahn, D. (2015)
CDiff: Systembiologie, Toxine und Epidemiologie von Clostridium difficile
BIOspektrum, 05:490-492

Madigan, M.T., Martinko, J.M., Stahl, D. & Clark, D.P. (2015)
Brock Mikrobiologie kompakt
(Ed. & Hrsg. Jahn, M. & Jahn, D.) Pearson Studium, Hallbergmoos, Germany.

2013

Peer reviewed articles

PUBMED: 23974024
Ebert, M.*, Laaß, S.*, Burghartz, M., Petersen, J., Koßmehl, S., Wöhlbrand, L., Rabus, R., Wittmann, C., Tielen, P. & Jahn, D. (2013)
Transposon mutagenesis identified chromosomal and plasmid encoded genes essential for the adaptation of the marine bacterium Dinoroseobacter shibaeto anaerobic conditions.
J Bacteriol., 195:4769-4777

*contributed equally to this work

PUBMED: 23823498
Patzelt, D., Wang, H., Buchholz, I., Rohde, M., Gröbe, L., Pradella, S., Neumann, A., Schulz, S., Heyber, S., Münch, K., Münch, R., Jahn, D., Wagner-Döbler, I. & Tomasch, J. (2013)
You are what you talk: quorum sensing induces individual morphologies and cell division modes in Dinoroseobacter shibae
ISME J., 7:2274-2286

PUBMED: 23967252
Tielen, P., Rosin, N., Dohnt, K., Haddad, I., Jänsch, L., Klein J., Meyer, A.-K., Narten, M., Pommerenke, C., Scheer, M., Schobert., M., Schomburg, D. & Jahn, D. (2013)
Regulatory and metabolic networks for the adaptation of Pseudomonas aeruginosa biofilms to urinary tract-like conditions
PLOS ONE 8: e71845. doi:10.1371/journal.pone.0071845

PUBMED: 23695583
Frädrich, C., Krausze, J., Quade, N., Schubert, M., Heinz, D.W., Jahn, D. & Härtig, E. (2013)
Purification, crystallization and preliminary X-ray analysis of the effector domain of AlsR, a LysR-type transcriptional regulator of Bacillus subtilis
Acta crystallographica Section F, 69:581-584

PUBMED: 23363548
Kaufholz, A.-L., Hunter, G. A., Ferreira, G. A., Lendrihas, T., Hering, V., Layer, G., Jahn, M. & Jahn D. (2013)
Aminolevulinic acid synthase of Rhodobacter capsulatus - high resolution kinetic investigation of the structural basis for substrate binding and catalysis
Biochem J., 451:205-216

PUBMED: 23341615
Moser, J., Lange, C., Krausze, J., Rebelein, J., Schubert, W.-D., Ribbe, M., Heinz, D.W. & Jahn, D. (2013)
Structure of ADP•AlF3-stabilized protochlorophyllide oxidoreductase complex
Proc Natl Acad Sci USA, 110:2094-2098

PUBMED: 23036925
Steen, A., Ütkür, F.Ö., Borrero-de Acuña, J.M., Bunk, B., Roselius, L., Bühler, B., Jahn, D. & Schobert, M. (2013)
Construction and characterization of nitrate and nitrite respiring Pseudomonas putida KT2440 strains for anoxic biotechnical applications
J Biotechnol., 163:155-165

PUBMED: 22750448
Korneli, C., David, F., Biedendieck, R., Jahn, D. & Wittmann, C. (2013)
Getting the big beast to work--systems biotechnology of Bacillus megaterium for novel high-value proteins
J Biotechnol. 163: 87-96.

PUBMED: 23179620
Korneli, C., Biedendieck, R., David, F., Jahn, D. & Wittmann, C. (2013)
High yield production of extracellular recombinant levansucrase by Bacillus megaterium
Appl Microbiol Biotechnol., 97:3343-3353

PUBMED: 23179618
Diekmann, N., Burghartz, M., Remus, L., Kaufholz, A.-L., Nawrath, T., Rohde, M., Schulz, S., Roselius, L., Schaper, J., Mamber, O., Jahn, D. & Jahn, M. (2013)
Microbial communities related to volatile organic compound emission in automobile air conditioning units
Appl Microbiol Biotechnol., 97: 8777-8793

Book articles and Reviews

Kaufholz, A.-L., Layer, G., Heinz, D., Jahn M. & Jahn, D. (2013)
The Structural Basis of Porphyrias - Defects of Heme Biosynthetic Enzymes
in Handbook of Porphyrin Science, Vol. 29, Ferreira, G. C., Kadish, K. M., Smith, K. M. (Eds.), p. 1 - 42, World Scientific Pub. Co. Pte. Ltd., Singapore.

2012

Peer reviewed articles

PUBMED: 23046954
Härtig, E. & Jahn, D. (2012)
Regulation of the Anaerobic Metabolism in Bacillus subtilis
Adv Microb Physiol., 61:195-216

PUBMED: 22772947
Klein, J., Leupold, S., Biegler, I., Biedendieck, R., Münch, R. & Jahn, D. (2012)
TLM-Tracker: Software for cell segmentation, tracking and lineage analysis in time-lapse microscopy movies
Bioinformatics, 28: 2276-2277
www.tlmtracker.tu-bs.de

PUBMED: 22178965
Frädrich, C., March, A., Fiege, K., Hartmann, A., Jahn, D. & Härtig, E. (2012)
The transcription factor AlsR binds and regulates the promoter of the alsSD operon responsible for acetoin formation in Bacillus subtilis
J Bacteriol., 194: 1100-1112

PUBMED: 22142238
Abicht, H.K., Martinez, J., Layer, G., Jahn, D. & Solioz, M. (2012)
Lactococcus lactis HemW (HemN) is a heme-binding protein with a putative role in heme trafficking
Biochem J., 442: 335-343

PUBMED: 22155866
Shevshuk, O., Roselius, L., Günther, G., Klein, J., Jahn, D., Steinert, M. & Münch, R. (2012)
InFiRe - a novel computational method for the identification of insertion sites in transposon mutagenized bacterial genomes
Bioinformatics, 28:306-310

Book articles and Reviews

Jahn, D., Krull, R. & Wittmann, C. (Eds.) (2012)
From gene to product - Development of biotechnological processes by integrating genetic and engineering methods. Concluding reports, collaborative research centre SFB 578.
Cuvillier Verlag, Göttingen 2012, ISBN 978-3-642-17305-9 2.

Jahn, M. & Jahn, D. (2012)
Electron transfer reactions and oxidative phosphorylation
in "Biochemical pathways: an atlas of biochemistry and molecular biology" Michal, G., Schomburg, D. (Eds.), John Wiley & Sons, p 183-187

Jahn, M. & Jahn, D. (2012)
Tetrapyrroles
in "Biochemical pathways: an atlas of biochemistry and molecular biology" Michal, G., Schomburg, D. (Eds.), John Wiley & Sons, p 82-92

Jahn, M. & Jahn, D. (2012)
Protein synthesis in bacteria
in "Biochemical pathways: an atlas of biochemistry and molecular biology" Michal, G., Schomburg, D. (Eds.), John Wiley & Sons, p 210-218.

Tielen, P., Schobert, M., Härtig, E. & Jahn, D. (2012)
Anaerobic regulatory networks in bacteria
in "Bacterial regulatory networks", Filloux, A. A. M. (Ed.), Horizon Academic Press, Norwich, UK, 273 - 305

Bröcker, M., Jahn, D. & Moser, J. (2012)
Key Enzymes of Chlorophyll Biosynthesis
in "Handbook of Porphyrin Science", 20, 1-43

2011

Peer reviewed articles

PUBMED: 21935588
Borgmeier, C., Biedendieck, R., Hoffmann, K., Jahn, D. & Meinhardt, F. (2011)
Transcriptome profiling of degU expression reveals unexpected regulatory patterns in Bacillus megaterium and discloses new targets for optimizing expression
Appl Microbiol Biotechnol., 92: 583-596

PUBMED: 21705586
Eppinger, M., Bunk, B., Johns, M.A., Edirisinghe, J.N., Kutumbaka, K.K., Koenig, S.S.K., Creasy, H.H., Rosovitz, M.J., Riley, D.R., Daugherty, S., Martin, M., Elbourne, L.D.H., Paulsen, I., Biedendieck, R., Braun, C., Grayburn, Dhingra, S., Lukyanchuk, V., Ball, B., ul-Qamar, R., Seibel, J., Bremer, E., Jahn, D., Ravel, J. & Vary, P.S. (2011)
Genome sequences of the biotechnologically important B. megaterium strains QM B1551 and DSM319
J Bacteriol. 193: 4199-4213

Piekarski, T., Jahn, D. & Tielen, P. (2011)
Marine Mikrobiologie: Etablierung genetischer Werkzeuge für Bakterien der Roseobacter-Gruppe.
BIOspektrum 04/11

PUBMED: 21454585
Strube, C.P., Homann, A., Gamer, M., Jahn, D., Seibel, J. & Heinz, D.W. (2011)
Polysaccharide synthesis of the levansucrase SACB from Bacillus megaterium is controlled by distinct surface motifs.
J Biol Chem. 286: 17593-17600

PUBMED: 21392131
Hebecker, S., Arendt, W., Heinemann, I.U., Tiefenau, J.H.J., Nimtz, M., Rohde, M., Söll, D., & Moser, J.. (2011)
Alanyl-Phosphatidylglycerol Synthase: Mechanism of Substrate Recognition during tRNA-dependent Lipid Modification in Pseudomonas aeruginosa.
Mol Microbiol.80: 935-950

PUBMED: 21943898
Biedendieck, R., Borgmeier, C., Bunk, B., Stammen, S., Scherling, C., Meinhardt, F., Wittmann, C. & Jahn, D. (2011)
Systems biology of recombinant protein production using Bacillus megaterium.
Methods Enzymol., 500: 165-195

PUBMED: 21219871
De Armas-Ricard, M., Levicán, G., Katz, A., Moser, J., Jahn, D. & Orellana, O. (2011)
Cellular levels of heme affect the activity of glutamyl-tRNA reductase.
Biochem. Biophys. Res. Com., 405: 134-139

PUBMED: 21310745
Bartsch, A., Bunk, B., Haddad, I., Klein, J., Münch, R., Johl, T., Kärst, U., Jänsch, L., Jahn, D. & Retter, I. (2011)
GeneReporter - Sequence based document retrieval andannotation
Bioinformatics, 27: 1034-1035

PUBMED: 21110836
Garbe, J., Wesche, A., Bunk, B., Kazmierczak, M., Selezska, K., Rohde, C., Sikorski, J., Rohde, M., Jahn, D. & Schobert, M. (2011)
Characterization of JG024, a Pseudomonas aeruginosa PB1- like broad host range phage under simulated infection conditions.
BMC Microbiol., 10:301

Book articles and Reviews

Münch, R., Klein, J. & Jahn, D. (2011)
Bookchapter: Prediction and Analysis of Gene Regulatory Networks in Prokaryotic Genomes. Bioinformatics - Experimental Biology Systems ISBN 978-953-307-280-7. InTech - Open Access Publisher

2010

Peer reviewed articles

PUBMED: 21068385
Gruner, I, Frädrich, C, Böttger H.L., Trautwein, A.X., Jahn, D. & Härtig, E. (2010)
Aspartate 141 it the fourth ligand of the oxygen sensing [4Fe-4S]2+ cluster of Bacillus subtilis transcriptional regulator Fnr
J. Biol. Chem., 286:2017-2021

PUBMED: 20951638
Schobert, M. & Jahn, D. (2010)
Anaerobic physiology of Pseudomonas aeruginosa in the cystic fibrosis lung.
Int. J. Med. Microbiol., 300:549-456

PUBMED: 21193347
Tielen, P., Narten, M., Rosin, N., Biegler, I., Haddad, I., Hogardt, M., Neubauer, R., Schobert, M., Wiehlmann, L. & Jahn, D. (2010)
Genotypic and phenotypic characterization of Pseudomonas aeruginosa isolates from urinary tract infections.
Int. J. Med. Microbiol., 301: 282-292

PUBMED: 21197080
Storbeck, S., Rolfes, S., Raux-Deery, E., Warren, M.J., Jahn, D. & Layer, G. (2010)
A novel pathway for the biosynthesis of heme in Archaea: Genome-based bioinformatic predictions and experimental evidence.
Archaea 2010, ID 175050

PUBMED: 20670661
David, F., Westphal, R., Bunk, B., Jahn, D. & Franco-Lara, E. (2010)
Optimization of antibody fragment production in Bacillus megaterium: the role of metal ions on protein secretion.
J Biotechnol. 150:115-124.

PUBMED: 20823549
Haffke, M., Menzel, A., Carius, Y., Jahn, D. & Heinz, D.W. (2010)
Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides.
Acta Cryst. 66:979-987

PUBMED: 20546309
Rosenau, F., Isenhardt, S., Gdynia, A., Tielker, D., Schmidt, E., Tielen, P., Schobert, M., Jahn, D., Wilhelm, S. & Jaeger, K.E. (2010)
Lipase LipC affects motility, biofilm formation and rhamnolipid production in Pseudomonas aeruginosa.
FEMS Microbiol Lett. 309:25-34.

PUBMED: 20596705
Stammen, S., Schuller, F., Dietrich, S., Gamer, M., Biedendieck, R. & Jahn, D. (2010)
Application of Escherichia coli phage K1E DNA-dependent RNA polymerase for in vitro RNA synthesis and in vivo protein production in Bacillus megaterium.
Appl. Microbiol. Biotechnol. 88: 529-539

PUBMED: 20553007
Silva, P., Schulz, C., Jahn, M., Jahn, D. & Ramos, M. (2010) A Tale of two acids: When arginine is a more appropriate acid than H₃O⁺.
J Phys Chem 114: 8994-9001

PUBMED: 20558746
Bröcker, M., Schomburg, S., Heinz, D.W., Jahn, D., Schubert, W.D. & Moser, J. (2010)
Crystal structure of the nitrogenase-like dark operative protochlorophyllide oxidoreductase catalytic complex (ChlN/ChlB)2.
J. Biol Chem 285:27336-27345

PUBMED: 20484676
Möbius, K., Arias-Cartin, R., Breckau, D., Haennig, A.-L., Riedmann, K., Biedendieck, R., Schroeder, S., Becher, D., Magalon, A., Moser, J., Jahn, M. & Jahn, D. (2010)
Heme biosynthesis is coupled to electron transport chains for energy generation
Proc. Natl. Acad. Sci. USA 107:10436-10441.

PUBMED: 20435764
Stammen, S., Müller, B.K., Korneli, C., Biedendieck, R., Gamer, M., Franco-Lara, E. & Jahn, D. (2010)
High yield intra- and extracellular protein production using Bacillus megaterium
Appl. Environ. Microbiol. 76: 4037-4046

PUBMED: 20506125
Layer, G., Reichelt, J., Jahn, D. & Heinz, D.W. (2010)
Structure and function of enzymes in heme biosynthesis
Protein Science 19, 1137-1161

PUBMED: 20553552
Trunk, K., Benkert, B., Quaeck, N., Muench, R., Scheer, M., Garbe, J., Jaensch, J., Trost, M., Wehland, J., Buer, J., Jahn, M., Schobert, M. & Jahn, D. (2010)
Anaerobic adaptation in Pseudomonas aeruginosa: Definition of the Anr and Dnr Regulons.
Environ. Microbiol. 12, 1719-1733

PUBMED: 20075073
Bröcker, M., Wätzlich, D., Saggu, M., Lendzian, F., Moser, J. & Jahn, D. (2010)
Biosynthesis of (bacterio)chlorophylls: ATP-dependent transient subunit interaction and electron transfer of dark operative protochlorophyllide oxidoreductase.
J. Biol Chem 285: 8268-8277

PUBMED: 21326933
Bunk, B., Schulz, A., Stammen, S., Münch, R., Warren, M. J., Rohde, M., Jahn, D. & Biedendieck, R. (2010)
A short story about a big magic bug.
Bioengineered Bugs 1: 1-7

PUBMED: 21255303
Biedendieck, R., Malten, M., Barg, H., Bunk, B., Martens, J.-H., Deery, E., Leech, H., Warren, M. J. & Jahn, D. (2010)
Metabolic engineering of cobalamin (vitamin B₁₂) production in Bacillus megaterium.
Microbial Biotechnology 3: 24-37

Book articles and Reviews

Jahn, D., & Jahn, M. (2010)
Warum sind Bakterien unsere Freunde? In: Kinder-Uni Braunschweig-Wolfsburg (Sandhagen, P., Ed.), Westermann
Verlag Braunschweig, 13-30

PUBMED: 20140656
Biedendieck, R., Bunk, B., Fürch, T., Franco-Lara, E., Jahn, M. & Jahn, D. (2010)
Systems Biology of Recombinant Protein Production in Bacillus megaterium
in "Advances in Biochemical Engineering / Biotechnology"
(Scheper, T., Ed.); Biosystems Engineering (Wittmann, C., Ed.)
Springer, Berlin, Heidelberg 120: 133-161

Bunk, B., Biedendieck, R., Jahn, D. & Vary, P. S. (2010)
Bacillus megaterium and other Bacilli, Industrial Applications
In Flickinger M. C. (Ed.) Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology.
Volume 1 pp 429-443. John Wiley & Sons. Inc., Hoboken, NJ.

Layer, G., Jahn, D., Deery, E., Lawrence, A.D. & Warren, M. (2010)
Biosynthesis of heme and vitamin B12 in "Comprehensive natural products II Chemistry and Biology"
(Mander, L., Lui, H.-W.)
Elsevier: Oxford; 7:445-499

2009

Peer reviewed articles

PUBMED: 20021642
Piekarski, T., Buchholz, I., Drepper, T., Schobert, M., Wagner-Doebler, I., Tielen, P. & Jahn, D. (2009)
Genetic tools for the investigation of Roseobacter clade bacteria.
BMC Microbiology, 9: 265

PUBMED: 19822707
Heinemann, I.U., Schulz, C., Schubert, W.D., Heinz, D., Wang, Y.G., Kobashi, Y., Awa, Y., Wachi, M., Jahn, D. & Jahn, M. (2009)
Structure of the heme biosynthetic Pseudomonas aeruginosa porphobilinogen synthase in complex with the antibiotic alaremycin.
Antimicrobial Agents and Chemotherapy 54: 267-572

PUBMED: 19741735
Wagner-Döbler, I., Ballhausen, B., Baumgart, M., Brinkhoff, T., Buchholz, I., Bunk, B., Cypionka, H., Daniel, R., Drepper, T., Gerdts, G., Hahnke, S., Han, C., Jahn, D., Kalhoefer, D., Kiss, H., Klenk, H.-P., Kyrpides, N., Liebl, W., Liesegang, H., Meincke, L., Pati, A., Petersen, J., Piekarski, T., Pommerenke, C., Pradella, S., Pukall, R., Rabus, R., Stackebrandt, E., Thole, S., Thompson, L., Tielen, P., Tomasch, J., von Jan, M., Wanphrut, N., Wichels, A., Zech, H. & Simon, M. (2009)
The complete genome sequence of the algal symbiont Dinoroseobacter shibae; a hitchhiker`s guide to life in the sea.
ISME Journal 4:61-77

Beine, R., Valente, A.R., Biedendieck, R., Jahn, D. & Seibel, J. (2009)
Directed optimization of biocatalytic transglycosylation processes by the integration of genetic algorithms and fermentative approaches into a kinetic model.
Process Biochemistry 44: 1103-1114

PUBMED: 19336405
Wätzlich, D., Bröcker, M., Uliczka, F., Ribbe, M., Virus, S.; Jahn, D. & Moser, J. (2009)
Chimeric nitrogenase-like enzymes of (bacterio)chlorophyll biosynthesis.
J. Biol Chem 284:15530-15540

PUBMED: 20109147
Haddad, I., Hiller, K., Frimmersdorf, E., Benkert, B., Schomburg, D. & Jahn, D. (2009)
An Emergent Self-organizing Map Based Analysis Pipeline for Comparative Metabolome Studies.
In Silico Biology 9:149-162

PUBMED: 19308404
Gamer, M., Froede, D., Biedendieck, R., Stammen, S. & Jahn, D. (2009)
A T7 RNA polymerase-dependent gene expression system for Bacillus megaterium.
Appl Microbiol Biotechnol. 82:1195-1203

PUBMED: 19087229
Klein, S., Lorenzo, C., Hoffmann, S., Walther, J. M., Storbeck, S., Piekarski, T., Tindall, B. J., Wray, V., Nimtz, M. & Moser, J. (2009)
Adaptation of Pseudomonas aeruginosa to various conditions includes tRNA-dependent formation of alanyl-phosphatidylglycerol.
Mol Microbiol 71:551-565

PUBMED: 18974177
Grote, A., Klein, J., Retter, I., Haddad, I., Behling, S., Bunk, B., Biegler, I., Yarmolinetz, S., Jahn, D. & Münch, R. (2009)
PRODORIC (release 2009): a database and tool platform for the analysis of gene regulation in prokaryotes.
Nucleic Acids Res. Database issue D61-5

PUBMED: 19025572
Walther, J., Bröcker, M., Wätzlich, D., Nimtz, M., Rohde, M., Jahn, D. & Moser, J. (2009)
Protochlorophyllide: A new photosensitizer for the photodynamic inactivation of Gram-positive and Gram-negative bacteria.
FEMS Microbiol. Lett. 296:156-163

PUBMED: 18854354
Klein, J., Münch, R., Biegler, I., Haddad, I., Retter, I. & Jahn, D. (2009)
Strepto-DB, a database for comparative genomics of group A (GAS) and B (GBS) streptococci, implemented with the novel database platform 'Open Genome Resource' (OGeR)
Nucleic Acids Res. Database issue D494-8

Book articles and Reviews

Jahn, D. & Heinz, D.W. (2009)
Biosynthesis of 5-aminolevulinic acid
in Tetrapyrroles-Birth, life and death (Warren, M.J., Smith, A. G., Eds.)
Landes Bioscience, Austin, Texas, USA

Tielen, P., Hogardt, M., Schobert, M., Heesemann, J., & Jahn, D. (2009)
Systembiologie der Harnwegs- und Wundinfektion durch Pseudomonas aeruginosa
GENOMEXPRESS 3.09, 17-19

Schilling, M., Hempel, D.C., & Jahn, D. (2009)
Vom Gen zum Produkt - aber mit System
Spektrum der Wissenschaft 10/09, 34-41

Jahn, D., & Schomburg, D. (2009)
Quo vadis Systembiologie
BIOspektrum 15, 07.09, 810-811

Jahn, M. & Jahn, D. (2009)
Regulation und Systembiologie in "Taschenlehrbuch Biologie - Genetik"
(Munk, K., Ed.)
Thieme Verlag

Jahn, M. & Jahn, D. (2009)
Milk fat rancidity in "Handbook of Hydrocarbon and Lipid Microbiology"
(Timmis, KN, Ed.)
Springer Verlag, Berlin, Germany
 

2008

Jahn, M. & Jahn, D. (2008)
Anpassungsfähigkeit von Mikroorganismen in "Taschenlehrbuch Biologie - Mikrobiologie" (Munk, K., Rd.)
Thieme Verlag

Dersch, P. & Jahn, D. (2008)
Mikrobielle Genetik in "Taschenlehrbuch Biologie - Mikrobiologie" (Munk, K., Rd.)
Thieme Verlag

PUBMED: 19047738
Masoumi, A., Heinemann, I. U., Rohde, M., Koch, M., Jahn, M. & Jahn D. (2008)
Complex formation between Protoporphyrinogen IX Oxidase and Ferrochelatase during Heme Biosynthesis in Thermosynechococcus elongatus.
Microbiology. 154:3707-3714

PUBMED: 18693243
Bröcker, M., Wätzlich, D., Uliczka, F., Virus, S., Saggu, M., Lendzian, F., Scheer, H., Rüdiger, W., Moser, J. & Jahn, D. (2008)
Substrate Recognition of Nitrogenase-like Dark Operative Protochlorophyllide Oxidoreductase from Prochlorococcus marinus.
J. Biol. Chem. 283:29873-29881

PUBMED: 18832311
Benkert, B., Quäck, N., Schreiber, K., Jaensch, L., Jahn, D. & Schobert, M. (2008)
Nitrate responsive NarX-NarL represses arginine mediated induction of the Pseudomonas aeruginosa arginine fermentation arcDABC operon.
Microbiology. 154:3053-3060

PUBMED: 18440972
Klein, J., Leupold, S., Münch, R., Pommerenke, C., Johl, T., Kärst, U., Jänsch, L., Jahn, D. and Retter, I. (2008)
ProdoNet: identification and visualization of prokaryotic gene regulatory and metabolic networks.
Nucleic Acids Res. 36:W460-464

PUBMED: 18928204
Pommerenke, C., Gabriel, I., Bunk, B., Münch, R., Haddad, I., Tielen, P., Wagner-Döbler I. & Jahn D. (2008)
ROSY - a flexible and universal database and bioinformatics tool platform for Roseobacter related species.
In Silico Biol. 8:177-186

PUBMED: 18314007
Heinemann, I. U., Jahn, M. & Jahn, D. (2008)
The biochemistry of heme biosynthesis.
Arch Biochem Biophys. 474:238-251. Review

PUBMED: 18252716
Bröcker, M.J., Virus, S., Ganskow, S., Heathcote, P., Heinz, D.W., Schubert, W-D., Jahn, D. & Moser, J. (2008)
ATP-Driven Reduction by Dark-Operative Protochlorophyllide Oxidoreductase from Chlorobium tepidum Mechanistically Resembles Nitrogenase Catalysis.
J. Biol. Chem. 283:10559-10567

PUBMED: 18042043
Tan, F.-C., Cheng,Q., Saha, K., Heinemann, I. U., Jahn, M., Jahn D. & Smith, A.G. (2008)
Identification and characterization of the Arabidopsis gene encoding the tetrapyrrole biosynthesis enzyme uroporphyrinogen III synthase.
Biochem. J. 410:291-29

2007

PUBMED: 17826861
Fürch, T., Wittmann, C., Wang, W., Franco-Lara, E., Jahn, D. & Deckwer, W. D. (2007)
Effect of different carbon sources on central metabolic fluxes and the recombinant production of a hydrolase from Thermobifida fusca in Bacillus megaterium.
J. Biotechnol. 132:385-394

PUBMED: 17929881
Huot, J., Balg, C., Jahn, D., Moser, J., Émond, A., Blais, S, Chênevert, R. & Lapointe, J. (2007)
Mechanism of a GatCAB amidotransferase: aspartyl-tRNA synthetase increases its affinity for Asp-tRNAAsn, and novel aa-tRNA analogs are competitive inhibitors.
Biochemistry 46:13190-13198

PUBMED: 17697121
Lüer, C., Schauer, S., Virus, S., Schubert, W.D., Heinz, D.W., Moser, J.& Jahn, D. (2007)
Glutamate Recognition and Hydride Transfer by Escherichia coli Glutamyl-tRNA Reductase.
FEBS Journal 274:4609-4614

PUBMED: 17692983
Biedendieck, R., Gamer, M., Jaensch, L., Meyer, S., Rohde, M., Deckwer, W.-D. & Jahn, D. (2007)
A sucrose-inducible promoter system for the intra- and extracellular protein production in Bacillus megaterium.
J Biotechnol. 132:426-430

PUBMED: 17608626
Homann, A., Biedendieck, R., Goetze, S., Jahn, D. & Seibel, J. (2007)
Insights into polymer versus oligosaccharide synthesis: Mutagenesis and mechanistic studies of a novel levansucrase from Bacillus megaterium.
Biochem J. 407:189-198

PUBMED: 17619232
Bäumchen, C., Roth, A. H. F. J., Biedendieck, R., Malten, M., Follmann, M., Sahm, H., Bringer-Meyer, S. & Jahn, D. (2007)
D-Mannitol production by resting state whole cell biotransformation of D-fructose by heterologous mannitol and formate dehydrogenase genes expression in Bacillus megaterium.
Biotechnol J. 2:1408-1416

PUBMED: 17657486
Vary, P. S., Biedendieck, R., Fuerch, T., Meinhardt, F., Rohde, M., Deckwer, W.-D. & Jahn, D. (2007)
Bacillus megaterium - from simple soil bacterium to industrial protein production host.
Appl Microbiol Biotechnol. 76:957-967. Review

PUBMED: Link
Klawonn, F., Choi, C., Benkert, B., Thielen, B., Münch, R., Schobert, M., Schomburg, D. & Jahn, D. (2007)
A Likelihood Ratio Test for Differential Metabolic Profiles in Multiple Intensity Measurements.
KES2007 Invited Sessions k07is-136

PUBMED: 17400734
Schreiber, K., Krieger, R., Benkert, B., Eschbach, M., Arai, H., Schobert, M. & Jahn, D. (2007)
The anaerobic regulatory network required for Pseudomonas aeruginosa nitrate respiration.
J Bacteriol. 189:4310-4314

PUBMED: Link
Choi, C., Münch, R., Bunk, B., Barthelmes, J., Ebeling, C., Schomburg, D., Schobert, M. & Jahn, D. (2007)
Combination of a data warehouse concept with web services for the establishment of the Pseudomonas systems biology database SYSTOMONAS.
Journal of Integrative Bioinformatics 4:48

PUBMED: 17224052
Jordan, E., Hust, M., Roth, A., Biedendieck, R., Schirrmann, T., Jahn, D. & Duebel, S. (2007)
Production of recombinant antibody fragments in Bacillus megaterium.
Microb Cell Fact. 6:2

PUBMED: 17134376
Heinemann, I.U., Diekmann, N., Masoumi, A., Koch, M., Messerschmidt, A., Jahn, M. & Jahn, D. (2007)
Functional definition of the tobacco protoporphyrinogen IX oxidase substrate binding site.
Biochem J. 402:575-580

PUBMED: 17245578
Biedendieck, R., Beine, R., Gamer, M., Jordan, E., Buchholz, K., Seibel, J., Dijkhuizen, L., Malten, M. & Jahn, D. (2007)
Export, purification and activities of affinity tagged Lactobacillus reuteri levansucrase produced by Bacillus megaterium.
Appl Microbiol Biotechnol. 74:1062-1073

PUBMED: 16948171
Yang, Y., Malten, M., Grote, A., Jahn, D. & Deckwer, W.D. (2007)
Codon optimized Thermobifida fusca hydrolase secreted by Bacillus megaterium.
Biotechnol Bioeng. 96:780-794

PUBMED: 16964623
Biedendieck, R., Yang, Y., Deckwer, W.-D., Malten, M. & Jahn, D. (2007)
Plasmid system for the intracellular production and purification of affinity-tagged proteins in Bacillus megaterium.
Biotechnol Bioeng. 96, 525-537

PUBMED: 17202169
Choi, C., Muench, R., Leupold, S., Klein, J., Siegel, I., Thielen, B., Benkert, B., Kucklick, M., Schobert, M., Barthelmes, J., Ebeling, C., Haddad, I., Scheer, M., Grote, A., Hiller, K., Bunk, B., Schreiber, K., Retter, I., Schomburg, D. & Jahn, D. (2007)
SYSTOMONAS - an integrated database for systems biology analysis of Pseudomonas.
Nucleic Acid Res. 35(Database Issue), D533-D537

2006

Jahn, D., Moser, J., Schubert, W. & Heinz, D (2006)
Transfer RNA-dependent aminolevulinic acid formation of glutamyl-tRNA synthetase, reductase and glutamate-1-semialdehyde-2,1-aminomutase, Vol. 25, B. Grimm, R. Porra, W. Rüdiger, H. Scheer (eds.) Chlorophylls and Bacteriochlorophylls: Biochemistry, Biophysics, Functions and Applications, pp. 445-459. Springer, Dordrecht, The Netherlands

PUBMED: 17132166
Yang, Y., Biedendieck, R., Wang, W., Gamer, M., Malten, M., Jahn, D. & Deckwer, W.-D. (2006)
High yield recombinant penicillin G amidase production and export into the growth medium using Bacillus megaterium.
Microb Cell Fact. 5:36

PUBMED: 17046977
Bunk, B., Kucklick, M., Jonas, R., Munch, R., Schobert, M., Jahn, D. & Hiller, K. (2006)
MetaQuant: a tool for the automatic quantification of GC/MS based metabolome data.
Bioinformatics. 22, 2962-2965

PUBMED: 17028275
Buchenau, B., Kahnt, J., Heinemann, I.U., Jahn, D. & Thauer, R.K. (2006)
Heme biosynthesis in Methanosarcina barkeri via a pathway involving two methylation reactions.
J Bacteriol. 188, 8666-8668

PUBMED: 16885274
Haertig, E., Hartmann, A., Schatzle, M., Albertini, A.M. & Jahn, D. (2006)
The Bacillus subtilis nrdEF genes, encoding a class Ib ribonucleotide reductase, are essential for aerobic and anaerobic growth.
Appl Environ Microbiol. 72, 5260-5265

PUBMED: 16876193
Schulze, J.O., Masoumi, A., Nickel, D., Jahn, M., Jahn, D., Schubert, W.D. & Heinz D.W. (2006)
Crystal Structure of a Non-discriminating Glutamyl-tRNA Synthetase.
J Mol Biol. 361, 888-897

PUBMED: 16870933
Hiller, K., Grote, A., Maneck, M., Muench, R. & Jahn, D. (2006)
JVirGel 2.0: computational prediction of proteomes separated via two dimensional gel electrophoresis under consideration of membrane and secreted proteins.
Bioinformatics 22, 2441-2443

PUBMED: 16845060
Scheer, M., Klawonn, F., Muench, R., Grote, A., Hiller, K., Choi, C., Koch, I., Schobert, M., Haertig, E., Klages, U. & Jahn, D. (2006)
JProGO: A novel tool for the functional interpretation of prokaryotic microarray data using Gene Ontology information.
Nucleic Acids Res. 34, 510-515

PUBMED: 16796679
Reents, H., Gruner, I., Harmening, U., Böttger, L.H., Layer, G., Heathcote, P., Trautwein, A.X., Jahn,D. & Haertig, E. (2006)
Bacillus subtilis Fnr senses oxygen via a [4Fe-4S]-cluster coordinated by three cysteine residures without change in the oligomeric state.
Mol. Microbiol. 60, 1432-1445

PUBMED: 16606627
Layer, G., Pierik, A.J., Trost, M., Rigby, S.E., Leech, H.K., Grage, K., Breckau, D., Astner, I., Jaensch, L., Heathcote, P., Warren, M.J., Heinz, D.W. & Jahn,D. (2006)
The substrate radical of Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN.
J. Biol. Chem. 281. 15272-15734

PUBMED: 16567015
Sun, J., Wang, W., Hundertmark, C., Zeng, A.P., Jahn, D. & Deckwer, W.D. (2006)
A protein database constructed from low-coverage genomic sequence of Bacillus megaterium and its use for accelerated proteomic analysis.
J. Biotechnol. 124, 486-495

PUBMED: 16564539
Schulze, J.O., Schubert, W.D., Moser, J., Jahn, D. & Heinz, D.W. (2006)
Evolutionary Relationship between Initial Enzymes of Tetrapyrrole Biosynthesis.
J. Mol. Biol. 358, 1212-1220

PUBMED: 16461726
Malten, M., Biedendieck, R., Gamer, M., Drews, A.C., Stammen, S., Buchholz, K., Dijkhuizen, L. & Jahn D (2006)
A Bacillus megaterium plasmid system for the production, export, and one-step purification of affinity-tagged heterologous levansucrase from growth medium.
Appl. Environ. Microbiol. 72, 1677-1679

Deckwer, W.-D., Hempel, D.C., Zeng, A.-P. & Jahn D (2006)
Systembiotechnologische Ansätze zur Prozessentwicklung.
Chemie Ingenieur Technik 78, 193-208

Hollmann, R., Malten, M., Biedendieck, R., Yang, Y., Wang, W., Jahn, D. & Deckwer, W.-D. (2006)
Bacillus megaterium als Produktionssystem für rekombinante Proteine.
Chemie Ingenieur Technik 78, 289-294

PUBMED: 16428414
Reents, H., Muench, R., Dammeyer, T., Jahn, D. & Haertig, E. (2006)
The Fnr Regulon of Bacillus subtilis.
J. Bacteriol. 188, 1103-111

2005

PUBMED: 16109747
Muench, R., Hiller, K., Grote, A., Scheer, M., Klein, J., Schobert, M. & Jahn, D. (2005)
Virtual Footprint and PRODORIC: an integrative framework for regulon prediction in prokaryotes.
Bioinformatics 21, 4187-4189

PUBMED: 16218869
Layer, G., Kervio, E., Morlock, G., Heinz, D.W., Jahn, D., Retey, J. & Schubert, W.D. (2005)
Structural and functional comparison of HemN to other radical SAM enzymes.
Biol Chem. 386, 971-980. Review

PUBMED: 16121195
Astner, I., Schulze, J.O., van den Heuvel, J., Jahn, D., Schubert, W.D. & Heinz DW. (2005)
Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.
EMBO J. 24, 3166-3177

PUBMED: 15967800
Layer, G., Grage, K., Teschner, T., Schunemann, V., Breckau, D., Masoumi, A., Jahn, M., Heathcote, P., Trautwein, A.X. & Jahn, D. (2005)
Radical S-Adenosylmethionine Enzyme Coproporphyrinogen III Oxidase HemN: FUNCTIONAL FEATURES OF THE [4Fe-4S] CLUSTER AND THE TWO BOUND S-ADENOSYL-L-METHIONINES.
J. Biol. Chem. 280, 29038-29046

PUBMED: 15927046
Wang, W., Hollmann, R., Furch, T., Nimtz, M., Malten, M., Jahn, D. & Deckwer W.D. (2005)
Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase.
Proteome Sci. 3, 4

PUBMED: 15980527
Grote, A., Hiller, K., Scheer, M., Muench, R., Noertemann, B., Hempel, D.C. & Jahn D. (2005)
JCat: a novel tool to adapt codon usage of a target gene to its potential expression host.
Nucleic Acids Res. 33, 526-531

PUBMED: 15757895
Lüer, C., Schauer, S., Moebius, K., Schulze, J., Schubert, W.-D., Heinz, D.W., Jahn, D. & Moser J.(2005)
Complex formation between glutamyl-tRNA reductase and glutamate-1-semialdehyde-2,1-aminomutase in Escherichia coli during the initial reaction of porphyrin biosynthesis.
J. Biol. Chem. 280, 18568-18572

PUBMED: 16003778
Malten, M., Nahrstedt, H., Meinhardt, F. & Jahn, D. (2005)
Coexpression of the type I signal peptidase gene sipM increases recombinant protein production and export in Bacillus megaterium MS941.
Biotechnol. Bioeng. 91, 616-621

PUBMED: 15790858
Sauerwald, A., Zhu, W., Major, T.A., Herve, R., Palioura, S., Jahn, D., Whitman, W., Yates, J.R. 3rd., Ibba, M. & Soell, D. (2005)
RNA-dependent cysteine biosynthesis in archaea.
Science 207, 1969-1972

PUBMED: 15690044
Randau, L., Münch, R., Hohn, M., Jahn, D. & Soell, D. (2005)
Nanoarchaeum equitans creates functional tRNA from separate genes encoding their 5'- and 3'-halves.
Nature 433, 537-541

PUBMED: 15644204
Frere, F., Reents, H., Schubert, W.D., Heinz, D.W., and Jahn, D.(2005)
Tracking the evolution of porphobilinogen synthase metal dependence in vitro.
J. Mol. Biol. 345, 1059-1070

PUBMED: 15593264
Malten, M., Hollmann, R., Deckwer, W.-D. & Jahn, D. (2005)
Production and secretion of recombinant Leuconostoc mesenteroides dextransucrase DsrS in Bacillus megaterium.
Biotechnol. Bioeng. 89, 206-218

2004

PUBMED: 15450488
Layer, G., Heinz, D.W., Jahn, D., Schubert, W.D. (2004) Structure and function of radical SAM enzymes.
Curr. Opin. Chem. Biol. 8, 468-476. Review

PUBMED: 15375128
Haertig, E., Geng, H., Hartmann, A., Hubacek, A., Münch, R., Ye, R. W., Jahn, D. & Nakano M. M. (2004)
Bacillus subtilis ResD Induces Expression of the Potential Regulatory Genes yclJK upon Oxygen Limitation.
J. Bacteriol. 186, 6477-6484

PUBMED: 15194701
Randau, L., Schauer, S., Ambrogelly, A., Salazar, J. C., Moser, J., Sekine, S., Yokoyama, S., Soell, D. & Jahn, D. (2004) tRNA recognition by glutamyl-tRNA reductase.
J. Biol. Chem. 279, 34931-34937

PUBMED: 15231792
Eschbach, M., Schreiber, K., Trunk, K., Buer, J., Jahn, D. & Schobert, M. (2004)
Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation.
J. Bacteriol. 186, 4596-4604

PUBMED: 15215414
Hiller, K., Grote, A., Scheer, M., Muench, R. & Jahn, D. (2004) PrediSi: prediction of signal peptides and their cleavage positions.
Nucleic Acids Res. 32, 375-37

2003

Moser, J., Frere, F., Heinz, D. W., Jahn, D., and Schubert, W. (2003)
Glutamat auf Abwegen: Die tRNA-abhängige Tetrapyrrol-Biosynthese.
Biospektrum 2, 133-137

PUBMED: 14550647
Schauer, S., Lüer, C. & Moser, J. (2003)
Large Scale Production of Escherichia coli Glutamyl-tRNA Reductase.
Protein Expr. Purif. 31, 271-275

PUBMED: 14663086
Baysse, C., Matthijs, S., Schobert, M., Layer, G., Jahn, D. & Cornelis, P. (2003)
Co-ordination of iron acquisition, iron porphyrin chelation and iron-protoporphyrin export via the cytochrome c biogenesis protein CcmC in Pseudomonas fluorescens.
Microbiology 149, 3543-3552

PUBMED: 14633981
Layer, G., Moser, J., Heinz, D. W., Jahn, D. & Schubert, W. D. (2003)
Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes.
EMBO J. 22, 6214-6224

PUBMED: 13680202
Frankenberg, N., Moser, J. & Jahn, D. (2003)
Bacterial heme biosynthesis and its biotechnological application.
Appl. Microbiol. Biotechnol. 63, 115-127. Review

PUBMED:12975365
Breckau, D., Mahlitz, E., Sauerwald, A., Layer, G. & Jahn, D. (2003)
Oxygen-dependent coproporphyrinogen III oxidase (HemF) from Escherichia coli is stimulated by manganese.
J. Biol. Chem. 278, 46625-46631

PUBMED:12917443
Leech, H. K., Raux, E., McLean, K. J., Munro, A. W., Robinson, N. J., Borrelly, G. P., Malten, M., Jahn, D., Rigby, S. E., Heathcote, P. & Warren, M. J. (2003)
Characterization of the cobaltochelatase CbiXL: evidence for a 4Fe-4S center housed within an MXCXXC motif.
J. Biol. Chem. 278, 41900-41907

PUBMED: 12824438
Hiller, K., Schobert, M., Hundertmark, C., Jahn, D. Muench, R. (2003)
JVirGel: Calculation of virtual two-dimensional protein gels.
Nucleic Acids Res. 31, 3862-3865

PUBMED: 12829291
Eschbach, M., Mobitz, H., Rompf, A. & Jahn, D. (2003)
Members of the genus Arthrobacter grow anaerobically using nitrate ammonification and fermentative processes: anaerobic adaptation of aerobic bacteria abundant in soil.
FEMS Microbiol. Lett. 223, 227-230.

PUBMED: 12408752
Raux, E., Leech, H. K., Beck, R., Schubert, H. L., Santander, P. J., Roessner, C. A., Scott, A. I., Martens, J. H., Jahn, D., Thermes, C., Rambach, A. & Warren, M. J. (2003)
Identification and functional analysis of enzymes required for precorrin-2 dehydrogenation and metal ion insertion in the biosynthesis of sirohaem and cobalamin in Bacillus megaterium.
Biochem J. 370, 505-516

PUBMED: 12519998
Muench, R., Hiller, K., Barg, H., Heldt, D., Linz, S., Wingender, E. & Jahn, D. (2003)
PRODORIC: Prokaryotic Database of Gene Regulation.
Nucleic Acids Res. 31, 266-26

2002

PUBMED: 12520026
Finking, R., Solsbacher, J, Konz, D., Schobert, M., Schafer, A., Jahn, D. & Marahiel, M. A. (2002)
Characterization of a new type of phosphopantetheinyl transferase for fatty acid and siderophore synthesis in Pseudomonas aeruginosa.
J. Biol. Chem. 277, 50293-50302

PUBMED: 12196141
Moser, J., Schubert, W. D., Heinz, D. W. & Jahn, D. (2002)
Structure and function of glutamyl-tRNA reductase involved in 5-aminolaevulinic acid formation.
Biochem. Soc. Trans. 30, 579-584

PUBMED: 12073043
Krieger, R., Rompf, A., Schobert, M. & Jahn, D. (2002)
The Pseudomonas aeruginosa hemA promoter is regulated by Anr, Dnr, NarL and integration host factor.
Mol. Gen. Genet. 267, 409-417

Schubert, W. D., Moser, J. Schauer, S., Heinz, D. & Jahn, D. (2002)
Structure and function of glutamyl-tRNA reductase, the first enzmye of tetrapyrrole biosynthesis in plants and prokaryotes.
Photosynthesis Res., 74, 205-210

PUBMED: 12370189
Schauer, S., Chaturvedi, S., Randau, L., Moser, J., Kitabatake, M., Lorenz, S., Verkamp, E., Schubert, W. D., Nakayashiki, T., Murai, M., Wall, K., Thomann, H. U., Heinz, D. W., Inokuchi, H., Soell, D. & Jahn, D. (2002)
Escherichia coli glutamyl-tRNA reductase: Trapping of the thioester intermediate.
J. Biol. Chem., 277, 48657-48663

Löhbach, C., Bakowsky, U., Kneuer, C., Jahn, D., Graeter, T., Schäfers, H.-J. & Lehr, C.-M. (2002)
Wet chemical modification of PTFE implant surfaces with specific cell adhesion molecule.
Chem. Comm. 21, 2568-2569

PUBMED: 12114526
Layer, G., Verfurth, K., Mahlitz, E. & Jahn, D. (2002)
Oxygen-independent Coproporphyrinogen-III Oxidase HemN from Escherichia coli.
J. Biol. Chem. 277, 34136-34142.

PUBMED: 12196141
Moser, J., Schubert, W. D., Heinz, D. W. & Jahn, D. (2002)
Structure and function of glutamyl-tRNA reductase involved in 5-aminolaevulinic acid formation.
Biochem. Soc. Transac. 30, 579-584

PUBMED: 12079382
Frere, F., Schubert, W. D., Stauffer, F., Frankenberg, N., Neier, R., Jahn, D. & Heinz, D. W. (2002)
Structure of Porphobilinogen Synthase from Pseudomonas aeruginosa in Complex with 5-Fluorolevulinic Acid Suggests a Double Schiff Base Mechanism.
J. Mol. Biol. 320, 237-247

PUBMED: 11931560
Schobert, M. & Jahn, D. (2002) Regulation of heme biosynthesis in non-phototrophic bacteria.
J. Mol. Microbiol. Biotechnol. 4, 287-294. Review

PUBMED: 11935176
Martens, J.-H., Barg, H., Warren, M. J. & Jahn, D. (2002) Microbial Production of Vitamin B₁₂.
Appl. Microbiol. Biotechnol. 58, 275-285. Revie

2001

PUBMED: 11726494
Moser, J., Schubert, W., Beier, V., Bringemeier, I., Jahn, D. & Heinz, D. W. (2001)
V-shaped Structure of Glutamyl-tRNA-Reductase, the first Enzyme of tRNA-Dependent Tetrapyrrole Biosynthesis.
EMBO. J. 20, 6583-6590

PUBMED: 11698370
Marino, M., Cruz-Ramos, H., Hoffmann, T., Glaser, P. & Jahn, D. (2001)
Modulation of Anaerobic Energy Metabolism of Bacillus subtilis by arfM (ywiD).
J. Bacteriol. 183, 6815-6821

PUBMED: 11931560
Schobert, M. & Jahn, D. (2001) Regulation of Heme Biosynthesis in Bacteria.
J. Mol. Microbiol. Biotechnol., 4, 287-29

2000

PUBMED: 10809684
Cruz-Ramos, H., Hoffmann, T., Marino, M., Nedjari, H., Presecan-Siedel, E., Dreesen, O., Glaser, P. & Jahn, D. (2000)
Fermentative metabolism of Bacillus subtilis: Physiology and regulation of gene expression.
J. Bacteriol. 182, 3072-3080

PUBMED: 10658656
Marino, M., Hoffmann, T., Mobitz, H., Schmid, R. & Jahn, D. (2000)
Changes in protein synthesis during the adaptation to anaerobic growth conditions in Bacillus subtilis.
Microbiology 146, 97-105

Jahn, D. (2000)
Anpassungsfähigkeit von Mikroorganismen.
In: Mikrobiologie - Lernbücher Biologie (K. Munk, Eds.). Spektrum, Akademischer Verlag
 

1999

PUBMED: 10498703
Homuth, G., Rompf, A. , Schumann, W. & Jahn, D. (1999)
Transcriptional control of Bacillus subtilis hemN and hemZ.
J. Bacteriol. 181, 5922-5929

PUBMED: 10521455
Moser, J., Lorenz, S. , Hubschwerlen, C., Rompf, A. & Jahn, D. (1999)
Methanopyrus kandleri glutamyl-tRNA reductase.
J. Biol. Chem. 274, 30679-30685

PUBMED: 10529244
Frankenberg, N., Jahn, D. & Jaffe, E. (1999)
Pseudomonas aeruginosa contains a novel type V porphobilinogen synthase with no required catalytic metal ions.
Biochemistry 38, 13976-13982

PUBMED: 10529243
Frankenberg, N., Heinz, D.W. & Jahn, D. (1999)
Production, purification and characterization of a Mg2+-responsive porphobilinogen synthase from Pseudomonas aeruginosa.
Biochemistry 38, 13968-13975

Frankenberg, N., Erskine, P.R., Cooper, J., Shoolingin-Jordan, P. M., Jahn, D. & Heinz, D. (1999)
High resolution crystal structure of a magnesium-dependent 5-aminolevulinic acid dehydratase.
J. Mol. Biol. 289, 591-602

Easson, E., Haltner, E., Lehr, C.-M., & Jahn, D. (1999)
Bacterial invasin factors as second generation bioadhesives.
In: Bioadhesive drug delivery systems: Fundamentals, novel approaches, and developments (Mathiowitz, E., Lehr, C-M., Chickering, D., Eds.). Begell House, Inc., New York, 405-433

Rompf, A. & Jahn, D. (1999)
Ecology of bacteria and fungi in foods: Influence of redox potential and pH.
In: Encyclopedia of Food Microbiology (Holland, T., Ed.), Academic Press Ltd., London, 556-562

1998

PUBMED: 9765565
Nakano, M.M., Hoffmann, T., Zhu, Y. & Jahn, D. (1998)
Nitrogen and oxygen regulation of Bacillus subtilis nasDEF encoding NADH-dependent nitrite reductase by TnrA and ResDE.
J. Bacteriol. 180, 5344-5350

Rajendran, N., Rompf, A., Marahiel, M.A. & Jahn, D. (1998)
Isolation and characterization of a transposon mutant of Pseudomonas fluorescens AU63 deficient in antifungal activity against Pythium ultimum.
Let. Appl. Microbiol. 27, 152-157

PUBMED: 9732527
Rompf, A., Schmid, R. & Jahn, D. (1998)
Changes in protein expression as a conseqeunce of heme depletion in Escherichia coli.
Curr. Microbiol. 37, 226-230

PUBMED: 9767567
Rompf, A., Hungerer, C., Hoffmann, T., A., Lindenmeyer, M., Romling, U., Gross, U., Doss, M.O., Arai, H., Igarashi, Y. & Jahn, D. (1998)
Regulation of Pseudomonas aeruginosa hemN and hemF by the dual action of the redox response regulators Anr and Dnr.
Mol. Microbiol. 29, 985-997

PUBMED: 9529530
Frankenberg, N., Hungerer, C., Kittel, T. & Jahn, D. (1998)
Cloning and characterisation of the Pseudomonas aeruginosa hemB encoding a magnesium-dependent aminolevulinic acid dehydratase.
Mol. Gen. Genet. 257, 485-489

PUBMED: 9396835
Lieb, C., Siddiqui, R. A., Hippler, B., Jahn, D. & Friedrich, B. (1998)
The Alcaligenes eutrophus hemN gene encoding the oxygen-independent coproporphyrinogen III oxidase is required for heme biosynthesis during anaerobic growth.
Arch. Microbiol. 169, 52-60

PUBMED: 9422613
Hoffmann, T., Frankenberg, N., Marino, M. & Jahn, D. (1998)
Ammonification in Bacillus subtilis utilizing dissimilatory nitrite reductase is dependent on resDE.
J. Bacteriol. 180, 186-18

1997

PUBMED: 9371469
Hippler, B., Homuth, G., Hoffmann, T., Schumann, W. & Jahn, D. (1997)
Characterization of Bacillus subtilis hemN.
J. Bacteriol. 179, 7181-7185

PUBMED: 9294458
Moebius, E., Jahn, M., Schmid, R., Jahn, D. & Maser, E. (1997)
Testosterone regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas testosteroni.
J. Bacteriol. 179, 5951-5955

Jahn, D. (1997)
Enzymatik und Regulation der Bildung bakterieller Tetrapyrrole.
Colloquia Academica der Akademie der Wissenschaften und Literatur Mainz, 43-74
 

1996

Easson, J.H., Hungerer, C., Jahn, D. & Lehr, C.-M. (1996)
Bioinvasive drug carrier systems for oral delivery of peptides and proteins.
Proc. Intern. Control Rel. Bioact. Mater. 23, 1000-1001

PUBMED: 8831980
Hungerer, C., Weiss, D., Thauer, R.K. & Jahn, D. (1996)
Cloning, characterization and expression of the Methanobacterium thermoautotrophicum hemA gene encoding glutamyl-tRNA reductase.
Bioorg. Med. Chem. 7, 1089-1095

Jahn, D., Hungerer, C. & Troup, B. (1996)
Ungewöhnliche Schritte und umweltregulierte Gene der bakteriellen Hämbiosynthese.
Naturwissenschaften 83, 389-400. Review

Jahn, D., Hungerer, C. & Troup, B. (1996)
Die bakterielle Hämbiosynthese: Alternative Wege und umweltgesteuerte Genexpression.
Biospektrum 2, 22-2

1995

PUBMED: 7557333
Hoffmann, T., Troup, B., Szabo, A., Hungerer, C. & Jahn, D. (1995)
The anaerobic life of Bacillus subtilis. Cloning and characterization of the genes encoding the respiratory nitrate reductase system.
FEMS Microbiol. Let. 131, 219-225

PUBMED: 7565600
Hungerer, C., Troup, B., Romling, U. & Jahn, D. (1995)
Cloning, mapping and characterization of the Pseudomonas aeruginosa hemL gene.
Mol. Gen. Genet. 248, 375-380

PUBMED: 7768836
Troup, B., Hungerer, C. & Jahn, D. (1995)
Cloning and characterization of the Escherichia coli hemN gene encoding the oxygen- independent coproporphyrinogen III oxidase.
J. Bacteriol. 177, 3326-3331

PUBMED: 7883699
Hungerer, C., Troup, B., Romling, U. & Jahn, D. (1995)
Regulation of the hemA gene during 5-aminolevulinic acid formation in Pseudomonas aeruginosa.
J. Bacteriol. 177, 1435-1443
 

1994

PUBMED: 8300522
Troup, B., Jahn, M., Hungerer, C. & Jahn, D. (1994)
Isolation of the hemF operon containing the gene for the Escherichia coli aerobic coproporphyrinogen III oxidase by in vivo complementation of a yeast HEM13 mutant.
J. Bacteriol. 176, 673-680

PUBMED: 8138133
Rajendran, N., Jahn, D., Jayaraman, K. & Marahiel, M.A. (1994)
Transposon Tn5 mutagenesis of Pseudomonas fluorescens to isolate mutants deficient in antibacterial activity.
FEMS Microbiol. Let. 115, 191-19

1992

Jahn, D., Verkamp, E. & Soell, D (1992)
Glutamyl-transfer RNA: a precursor of heme and chlorophyll biosynthesis.
Trends Biol. Sci. 17, 215-219. Review

Patents

Haddad, I., Münch, R. & Jahn, D. (2010)
Vorrichtung und System zur Durchführung von zeitaufgelösten Untersuchungen an Zellproben
DE: 10 2010 048 443.1 (Offengelegter Patentantrag)

Malten, M. & Jahn, D. (2003).
Produktion und Sekretion von Glucosyltransferasen.
DE: 102 25 380.3

Barg, H. & Jahn, D. (2003).
Verbessertes Verfahren zur Herstellung von Vitamin B₁₂
DE 103 00 719.9

Barg, H., Warren, M. J., Künkel, A. & Jahn, D. (2002).
Verbessertes Verfahren zur Herstellung von Vitamin B₁₂
DE 102 93 795.8

Barg, H., Warren, M. J., Künkel, A. & Jahn, D. (2002).
Verbessertes Verfahren zur Herstellung von Vitamin B₁₂
DE 101 50 323.7

Barg, H., Martens, J.-H., Warren, M. J., Künkel, A. & Jahn, D. (2001).
Optimierte Verfahren zur Herstellung von Vitamin B₁₂ mit Bacillus megaterium.
DE 101 50 359.8

Martens, J.-H., Barg, H., Warren, M. J., Künkel, A. & Jahn, D. (2001).
Verfahren zur Herstellung von Vitamin B₁₂ mit Bacillus megaterium.
DE 101 50 323.7