NaGa-PrinTOr

NaGa-PrinTOr - Nanoparticulate Gas-carriers for adjustable 3D-Printing of Tissues and Organs

Funding body: Federal Ministry of Education and Research

Contact persons: Pauline Breunig, Viktor Maurer

Project Summary:

Bioinks are materials that are used in the 3D printing of living tissue. However, current bioinks have several limitations that prevent the creation of bioactive tissue structures. The innovative core idea of this project is to integrate local gas depots in the form of gas vesicles into the bioinks to improve the cellular gas supply. This advancement enables the printing of complex functional tissue structures, which in future will allow drugs to be developed more quickly and synthetic transplant organs to be used. 

Objectives and Tasks of the iPAT:

• Microfluidic fabrication of organic nanoparticles with linker molecules on the particle surface
• Evaluation of oxygen encapsulation strategies within the nanoparticles
• Development of analytical measurement methods for testing oxygen encapsulation
• Co-encapsulation of additional substances (active ingredients, nutrients, magnetic nanoparticles, etc.) within the nanoparticles

Cooperation Partners:

• Blackdrop
•  Air Liquide