Structure-property relationships of antimicrobial polymers

A common and very challenging topic in nowadays research is the design of coatings for antimicrobial surfaces[1]. Antimicrobial surfaces are needed in a widespread field of applications that extends over food packaging, textiles, medical devices or water filtration systems[2]. The most challenging part in all application fields is to defeat the biofilm. The main focus of our research group is on using copolymers for medical devices[3]. In general, structure-property dependencies of antimicrobial polymers are currently highly investigated[4,5]. Recently, molecular weight and composition dependant properties as well as the molecular architecture were investigated with different copolymer systems[4]. But also photo-activate polymers are of great interest[6].

Schematic overview of possible structure dependant properties.

Literature

[1] a) J. Hasan, R. J. Crawford, E. P. Ivanova, Trends Biotechnol., 2013, 31, 295; b) S. Ferraris, S. Spriano, Mater. Sci. Eng. C, 2016, 61, 965; c) K. Bazaka, M. V. Jacob, W. Chrzanowski, K. Ostrikov, RSC Adv., 2015, 5, 48739.

[2] I. Banerjee, R. C. Pangule, R. S. Kane, Adv. Mater., 2011, 23, 690.

[3] Marco Waßmann, Dissertation: Anbindung von Copolymeren und Wirkstoffen zur Erzeugung von antibakteriellen Beschichtungen auf dentalen Implantaten, Dr. Hut, Technische Universität Braunschweig, 2015.

[4] R. Namivandi-Zangeneh, R. J. Kwan, T.-K. Nguyen, J. Yeow, F. L. Byrne, S. H. Oehlers, E. H. H. Wong, C. Boyer, Polym. Chem., 2018, 9, 1735.

[5] a) M. R. E. Santos, P. V. Mendonça, M. C. Almeida, R. Branco, A. C. Serra, P. V. Morais, J. F. J. Coelho, Biomacromolecules 2019, 20, 1146; b) X. Li, B. Wu, H. Chen, K. Nan, Y. Jin, L. Sun, B. Wang, J. Mater. Chem. B, 2018, 6, 4274.

[6] a) K. H. Hong, G. Sun, J. Appl. Polym. Sci., 2009, 112, 2019; b) A. Bilyk, S. Li, J. Murphy, S. Petinakis, K. Zerdin, A. Scully, Prog. Org. Coat., 2008, 62, 40.