Sustainable Mobility considers ground-based transport and air traffic as an overall system. Facing a global share of 24% of carbon-dioxide emissions due to transport systems based on fossil fuels, a new balance of technical, economic and ecological considerations is needed when designing the future means of transport. Disruptive technologies, such as “green” hydrogen, the electrification of drive/propulsion systems, and machine learning algorithms will contribute to shaping this paradigm shift of mobility. Beyond traffic simulation and aircraft/vehicle design, intermodal interaction of the transport systems must be incorporated into a sustainable mobility concept.