We are MedChem: The Frontiers in Medicinal Chemistry 2024. M. Schiedel, P. Barbie, F. Pape, M. Pinto, A. Unzue Lopez, M. Méndez, G. Hessler, D. Merk, M. Gehringer, C. Lamers. ChemMedChem (2024), e202400543. Impact factor: 3.540
Development of a NanoBRET assay platform to detect intracellular ligands for the chemokine receptors CCR6 and CXCR1. M.E. Huber, S.L Wurnig, A.F.A Moumbock, L. Toy, E. Kostenis, A. Alonso Bartolomé, M. Szpakowska, A. Chevigné, S. Günther, F.K. Hansen,# M. Schiedel.# ChemMedChem (2024), accepted article [#shared corresponding authorship]. https://doi.org/10.1002/cmdc.202400284. Impact factor: 3.540
Fluorophore-labeled pyrrolones targeting the intracellular allosteric binding site of the chemokine receptor CCR1. L. Toy, M.E. Huber, M. Lee, A. Alonso Bartolomé, N.V. Ortiz Zacarías, S. Nasser, S. Scholl, D.P. Zlotos, Y. M. Mandour, L.H. Heitman, M. Szpakowska, A. Chevigné, M. Schiedel. ACS Pharmacol. Transl. Sci. 7 (2024), 2080-2092. https://doi.org/10.1021/acsptsci.4c00182. Impact factor: 6.000
Development of a fluorescent ligand for the intracellular allosteric binding site of the neurotensin receptor 1. H. Vogt, P. Shinkwin, M.E. Huber, N. Staffen, H. Hübner, P. Gmeiner, M. Schiedel, Dorothee Weikert. ACS Pharmacol. Transl. Sci. 7 (2024), 1533-1545. https://pubs.acs.org/doi/10.1021/acsptsci.4c00086. Impact factor: 6.000
Development and initial characterization of the first 18F-CXCR2-targeting radiotracer for PET imaging of neutrophils. P. Spatz, X. Chen, K. Reichau, M.E. Huber, S. Mühlig, Y. Matsusaka, M. Schiedel, T. Higuchi, M. Decker. J. Med. Chem. 67 (2024), 6327-6343. https://doi.org/10.1021/acs.jmedchem.3c02285. Impact factor: 7.300