Prof. Dr. Sami Eldeeb
Prof. Dr. Sami Eldeeb (alternative Schreibweise El Deeb)
Institute of Medicinal and Pharmaceutical Chemistry
Technical University Braunschweig
Beethovenstr. 55
D-38106 Braunschweig
Germany
Tel.: 0531 - 391 7301
Fax. 0531 - 391 2799
2020-Present: Außerplanmäßiger Professor at Institute of Medicinal & Pharmaceutical Chemistry of TU Braunschweig, Germany.
2017-2019: PD Dr. at Institute of Medicinal & Pharmaceutical Chemistry of TU Braunschweig, Germany.
2014-2016: Senior researcher at Institute of Medicinal & Pharmaceutical Chemistry of TU Braunschweig, Germany.
2013-2014: Associated Professor at Faculty of Pharmacy of Al-Azhar University Gaza, Palestine.
2012-2013: Head of Drug Analysis & Research Center of Al-Azhar University Gaza, Palestine.
2010-2012: Postdoctoral fellow at Institute of Pharmacy of the Free University of Berlin, Germany.
2008-2010: Assistant Professor at Faculty of Pharmacy of Al-Azhar University Gaza, Palestine.
2004-2007: PhD study at Institute of Medicinal & Pharmaceutical Chemistry of TU Braunschweig, Germany.
2001-2003: MSc study at Faculty of Pharmacy, Jordan University Amman, Jordan.
1999-2001: Teaching assistant at Faculty of Pharmacy of Al-Azhar University Gaza, Palestine.
1994-1999: BSc Pharmacy study at Faculty of Pharmacy of Al-Azhar University Gaza, Palestine.
General research area is pharmaceutical instrumental analysis including lead compounds, pharmaceuticals and biopharmaceuticals characterization.
Particular research interest:
Binding affinity investigations (including drug-drug, drug-ion metals, drug- protein, protein-protein and drug-DNA) using microscale thermophoresis (MST), affinity chromatography (AC) and/or affinity capillary electrophoresis (ACE).
Development of Aptamer-based assay methods (including aptamers generation, aptamer affinity screening and aptamer based assay design e.g. aptasensor).
LC/MS drug characterization and metabolomics.
Organometallic anticancer analysis using high-resolution continuum-source atomic absorption spectrometry (HR-CS-AAS).
Fast HPLC method development and validation using monolithic columns (applying high flow rates, flow programming and column-to-column coupling) and/or using fused core columns.
Monolithic silica epoxy columns derivatization for the immobilization of new chiral selectors or affinity interactions.
Method development and validation using HILIC HPLC columns for polar solutes.
Bio-analysis of drugs from blood and/or urine samples after proper sample preparation using LC with fluorescence detection or using capillary electrophoresis.
Bioanalysis with direct serum injection (dilute and shoot) using shielded hydrophobic phase (Hisep HPLC column).
Enantiomeric drug separation and enantiomeric impurity determination (down to a concentration level of 0.1% or less relative to the main enantiomer) for quality control of chiral drugs using HPLC with chiral-based stationary phase (e.g. vancomycin-based HPLC column) or CE with different types of native and derivatized cyclodextrins and applying normal and reversed polarity modes.