PMID:31143408
Conrads G, Wendt LK, Hetrodt F, Deng ZL, Pieper D, Abdelbary MMH, Barg A, Wagner-Döbler I, Apel C. Deep sequencing of biofilm microbiomes on dental composite materials. J Oral Microbiol. 2019 May 14;11(1):1617013.
doi:10.1080/20002297.2019.1617013
PMID:31031742
Koppenhöfer S, Wang H, Scharfe M, Kaever V, Wagner-Döbler I, Tomasch J. Integrated Transcriptional Regulatory Network of Quorum Sensing, Replication Control, and SOS Response in Dinoroseobacter shibae. Front Microbiol. 2019 Apr 12;10:803.
doi:10.3389/fmicb.2019.00803
PMID: 30602652
Ziesche L, Wolter L, Wang H, Brinkhoff T, Pohlner M, Engelen B, Wagner-Döbler I, Schulz S. 2018. An Unprecedented Medium-Chain Diunsaturated N-acylhomoserine Lactone from Marine Roseobacter Group Bacteria. Mar Drugs 17:20.
DOI:10.3390/md17010020
PMID:29795276
Brinkmann H, Göker M, Koblížek M, Wagner-Döbler I, Petersen J. 2018. Horizontal operon transfer, plasmids, and the evolution of photosynthesis in Rhodobacteraceae. ISME J 12:1994–2010.
DOI:10.1038/s41396-018-0150-9
PMID:29261310
Bruns H, Herrmann J, Müller R, Wang H, Wagner Döbler I, Schulz S. 2018. Oxygenated N -Acyl Alanine Methyl Esters (NAMEs) from the Marine Bacterium Roseovarius tolerans EL-164. J Nat Prod 81:131–139.
DOI:10.1021/acs.jnatprod.7b00757
PMID:29875146
Deng Z-L, Gottschick C, Bhuju S, Masur C, Abels C, Wagner-Döbler I. 2018. Metatranscriptome Analysis of the Vaginal Microbiota Reveals Potential Mechanisms for Protection against Metronidazole in Bacterial Vaginosis. mSphere Jun 6;3(3). pii: e00262-18. doi: 10.1128/mSphereDirect.00262-18. Print 2018 Jun 27.
DOI:10.1128/mSphereDirect.00262-18
PMID:29467738
Deng Z-L, Sztajer H, Jarek M, Bhuju S, Wagner-Döbler I. 2018. Worlds Apart – Transcriptome Profiles of Key Oral Microbes in the Periodontal Pocket Compared to Single Laboratory Culture Reflect Synergistic Interactions. Front Microbiol 2018 Feb 6;9:124. doi: 10.3389/fmicb.2018.00124. eCollection 2018.
DOI:10.3389/fmicb.2018.00124
PMID:30022245
Kopejtka K, Tomasch J, Bunk B, Spröer C, Wagner-Döbler I, Koblížek M. 2018. The complete genome sequence of Rhodobaca barguzinensis alga05 (DSM 19920) documents its adaptation for life in soda lakes. Extremophiles 22:839–849.
DOI:10.1007/s00792-018-1041-8
PMID:29580208
Premnath P, Reck M, Wittstein K, Stadler M, Wagner-Döbler I. 2018. Screening for inhibitors of mutacin synthesis in Streptococcus mutans using fluorescent reporter strains. BMC Microbiol 18(1):24.
DOI:10.1186/s12866-018-1170-3
PMID:29325123
Tomasch J, Wang H, Hall ATK, Patzelt D, Preusse M, Petersen J, Brinkmann H, Bunk B, Bhuju S, Jarek M, Geffers R, Lang AS, Wagner-Döbler I. 2018. Packaging of Dinoroseobacter shibae DNA into Gene Transfer Agent Particles Is Not Random. Genome Biol Evol 10:359–369.
DOI:10.1093/gbe/evy005
PMID:28972613
Ammermann J, Schmidt T, Donner J, Reck M, Dalton M, Stumpp N, Stiesch M, Wagner-Döbler I, Kirschning A. 2017. The carolactam strategy is ineffective: synthesis and biological evaluation of carolactam. Org Biomol Chem 15:8553–8558.
DOI:10.1039/c7ob02060k
PMID:28389641
Beyersmann PG, Tomasch J, Son K, Stocker R, Göker M, Wagner-Döbler I, Simon M, Brinkhoff T. 2017. Dual function of tropodithietic acid as antibiotic and signaling molecule in global gene regulation of the probiotic bacterium Phaeobacter inhibens. Sci Rep 2017 Apr 7;7(1):730.
DOI:10.1038/s41598-017-00784-7
PMID:28371065
Bill N, Tomasch J, Riemer A, Müller K, Kleist S, Schmidt-Hohagen K, Wagner-Döbler I, Schomburg D. 2017. Fixation of CO 2 using the ethylmalonyl-CoA pathway in the photoheterotrophic marine bacterium Dinoroseobacter shibae. Environ Microbiol 19:2645–2660.
DOI:10.1111/1462-2920.13746
PMID:28623321
Deng Z-L, Szafrański SP, Jarek M, Bhuju S, Wagner-Döbler I. 2017. Dysbiosis in chronic periodontitis: Key microbial players and interactions with the human host. Sci Rep 7:3703.
DOI:10.1038/s41598-017-03804-8
PMID:28209832
Donner J, Bunk B, Schober I, Spröer C, Bergmann S, Jarek M, Overmann J, Wagner-Döbler I. 2017. Complete Genome Sequences of Three Multidrug-Resistant Clinical Isolates of Streptococcus pneumoniae Serotype 19A with Different Susceptibilities to the Myxobacterial Metabolite Carolacton. Genome Announc 2017 Feb 16;5(7). pii: e01641-16.
DOI:10.1128/genomeA.01641-16
PMID:28959742
Donner J, Reck M, Bunk B, Jarek M, App CB, Meier-Kolthoff JP, Overmann J, Müller R, Kirschning A, Wagner-Döbler I. 2017. The Biofilm Inhibitor Carolacton Enters Gram-Negative Cells: Studies Using a TolC-Deficient Strain of Escherichia coli. mSphere 2017 Sep 27;2(5). pii: e00375-17
DOI:10.1128/mSphereDirect.00375-17
PMID:29142318
Fu C, Sikandar A, Donner J, Zaburannyi N, Herrmann J, Reck M, Wagner-Döbler I, Koehnke J, Müller R. 2017. The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD. Nat Commun 8:1529.
DOI:10.1038/s41467-017-01671-5
PMID:28903767
Gottschick C, Deng Z-L, Vital M, Masur C, Abels C, Pieper DH, Rohde M, Mendling W, Wagner-Döbler I. 2017. Treatment of biofilms in bacterial vaginosis by an amphoteric tenside pessary - clinical study and microbiota analysis. Microbiome 5:119.
DOI:10.1186/s40168-017-0326-y
PMID:28807017
Gottschick C, Deng Z-L, Vital M, Masur C, Abels C, Pieper DH, Wagner-Döbler I. 2017. The urinary microbiota of men and women and its changes in women during bacterial vaginosis and antibiotic treatment. Microbiome 5:99.
DOI:10.1186/s40168-017-0305-3
Milici M, Vital M, Tomasch J, Badewien TH, Giebel HA, Plumeier I, Wang H, Pieper DH, Wagner-Döbler I, Simon M. 2017. Diversity and community composition of particle-associated and free-living bacteria in mesopelagic and bathypelagic Southern Ocean water masses: Evidence of dispersal limitation in the Bransfield Strait. Limnol Oceanogr 62:1080–1095.
https://doi.org/10.1002/lno.10487
PMID:28769910
Petersen J, Wagner-Döbler I. 2017. Plasmid Transfer in the Ocean – A Case Study from the Roseobacter Group. Front Microbiol 2017 Jul 18;8:1350.
DOI:10.3389/fmicb.2017.01350
PMID:28106881
Simon M, Scheuner C, Meier-Kolthoff JP, Brinkhoff T, Wagner-Döbler I, Ulbrich M, Klenk H-P, Schomburg D, Petersen J, Göker M. 2017. Phylogenomics of Rhodobacteraceae reveals evolutionary adaptation to marine and non-marine habitats. ISME J 11:1483–1499.
DOI:10.1038/ismej.2016.198
PMID:28320314
Szafrański SP, Deng Z-L, Tomasch J, Jarek M, Bhuju S, Rohde M, Sztajer H, Wagner-Döbler I. 2017. Quorum sensing of Streptococcus mutans is activated by Aggregatibacter actinomycetemcomitans and by the periodontal microbiome. BMC Genomics 18:238.
DOI:10.1186/s12864-017-3618-5
PMID:27404808
Donner J, Reck M, Bergmann S, Kirschning A, Müller R, Wagner-Döbler I. The biofilm inhibitor Carolacton inhibits planktonic growth of virulent pneumococci via a conserved target. Sci Rep. 2016 Jul 11;6:29677.
doi:10.1038/srep29677
PMID:27303368
Patzelt D, Michael V, Päuker O, Ebert M, Tielen P, Jahn D, Tomasch J, Petersen J, Wagner-Döbler I. Gene Flow Across Genus Barriers - Conjugation of Dinoroseobacter shibae's 191-kb Killer Plasmid into Phaeobacter inhibens and AHL-mediated Expression of Type IV Secretion Systems. Front Microbiol. 2016 May 31;7:742.
doi:10.3389/fmicb.2016.00742
PMID:27242711
Reck M, Wagner-Döbler I. Carolacton Treatment Causes Delocalization of the Cell Division Proteins PknB and DivIVa in Streptococcus mutans in vivo. Front Microbiol. 2016 May 11;7:684.
doi:10.3389/fmicb.2016.00684
PMID:27199970
Milici M, Deng ZL, Tomasch J, Decelle J, Wos-Oxley ML, Wang H, Jáuregui R, Plumeier I, Giebel HA, Badewien TH, Wurst M, Pieper DH, Simon M, Wagner-Döbler I. Co-occurrence Analysis of Microbial Taxa in the Atlantic Ocean Reveals High Connectivity in the Free-Living Bacterioplankton. Front Microbiol. 2016 May 6;7:649.
doi:10.3389/fmicb.2016.00649
PMID:27199923
Milici M, Tomasch J, Wos-Oxley ML, Decelle J, Jáuregui R, Wang H, Deng ZL, Plumeier I, Giebel HA, Badewien TH, Wurst M, Pieper DH, Simon M, Wagner-Döbler I. Bacterioplankton Biogeography of the Atlantic Ocean: A Case Study of the Distance-Decay Relationship. Front Microbiol. 2016 Apr 26;7:590.
doi:10.3389/fmicb.2016.00590
PMID:27169388
Wagner-Döbler I. Biofilm transplantation in the deep sea. Mol Ecol. 2016 May;25(9):1905-7.
doi:10.1111/mec.13612
PMID:27111438
Gottschick C, Szafranski SP, Kunze B, Sztajer H, Masur C, Abels C, Wagner-Döbler I. Screening of Compounds against Gardnerella vaginalis Biofilms. PLoS One. 2016 Apr 25;11(4):e0154086.
doi:10.1371/journal.pone.0154086
PMID:26807547
Cabarcas-Montalvo M, Maldonado-Rojas W, Montes-Grajales D, Bertel-Sevilla A, Wagner-Döbler I, Sztajer H, Reck M, Flechas-Alarcon M, Ocazionez R, Olivero-Verbel J. Discovery of antiviral molecules for dengue: In silico search and biological evaluation. Eur J Med Chem. 2016 Mar 3;110:87-97.
doi:10.1016/j.ejmech.2015.12.030
PMID:26750451
Milici M, Tomasch J, Wos-Oxley ML, Wang H, Jáuregui R, Camarinha-Silva A, Deng ZL, Plumeier I, Giebel HA, Wurst M, Pieper DH, Simon M, Wagner-Döbler I. Low diversity of planktonic bacteria in the tropical ocean. Sci Rep. 2016 Jan 11;6:19054.
doi:10.1038/srep19054
PMID:26574687
Gómez-Consarnau L, González JM, Riedel T, Jaenicke S, Wagner-Döbler I, Sañudo-Wilhelmy SA, Fuhrman JA. Proteorhodopsin light-enhanced growth linked to vitamin-B1 acquisition in marine Flavobacteria. ISME J. 2016 May;10(5):1102-12.
doi:10.1038/ismej.2015.196
PMID:26617596
Wang H, Tomasch J, Michael V, Bhuju S, Jarek M, Petersen J, Wagner-Döbler I. Identification of Genetic Modules Mediating the Jekyll and Hyde Interaction of Dinoroseobacter shibae with the Dinoflagellate Prorocentrum minimum. Front Microbiol. 2015 Nov 13;6:1262.
doi:10.3389/fmicb.2015.01262
PMID:26404611
Voget S, Bruns H, Wagner-Döbler I, Schulz S, Daniel R. Draft Genome Sequence of Roseovarius tolerans EL-164, a Producer of N-Acylated Alanine Methyl Esters and N-Acylhomoserine Lactones. Genome Announc. 2015 Sep 24;3(5). pii: e01096-15.
doi:10.1128/genomeA.01096-15
PMID:28721234
Szafrański SP, Deng ZL, Tomasch J, Jarek M, Bhuju S, Meisinger C, Kühnisch J, Sztajer H, Wagner-Döbler I. Functional biomarkers for chronic periodontitis and insights into the roles of Prevotella nigrescens and Fusobacterium nucleatum; a metatranscriptome analysis. NPJ Biofilms Microbiomes. 2015 Sep 23;1:15017.
doi:10.1038/npjbiofilms.2015.17
PMID:26212108
Ziesche L, Bruns H, Dogs M, Wolter L, Mann F, Wagner-Döbler I, Brinkhoff T, Schulz S. Homoserine Lactones, Methyl Oligohydroxybutyrates, and Other Extracellular Metabolites of Macroalgae-Associated Bacteria of the Roseobacter Clade: Identification and Functions. Chembiochem. 2015 Sep 1;16(14):2094-107.
doi:10.1002/cbic.201500189
PMID:26158727
Reck M, Tomasch J, Wagner-Döbler I. The Alternative Sigma Factor SigX Controls Bacteriocin Synthesis and Competence, the Two Quorum Sensing Regulated Traits in Streptococcus mutans. PLoS Genet. 2015 Jul 9;11(7):e1005353.
doi:10.1371/journal.pgen.1005353
PMID:26140923
Reck M, Tomasch J, Deng Z, Jarek M, Husemann P, Wagner-Döbler I; COMBACTE Consortium. Stool metatranscriptomics: A technical guideline for mRNA stabilisation and isolation. BMC Genomics. 2015 Jul 4;16:494.
doi:10.1186/s12864-015-1694-y
PMID:25902328
Stumpp N, Premnath P, Schmidt T, Ammermann J, Dräger G, Reck M, Jansen R, Stiesch M, Wagner-Döbler I, Kirschning A. Synthesis of new carolacton derivatives and their activity against biofilms of oral bacteria. Org Biomol Chem. 2015 May 28;13(20):5765-74.
doi:10.1039/c5ob00460h
PMID:25859246
Soora M, Tomasch J, Wang H, Michael V, Petersen J, Engelen B, Wagner-Döbler I, Cypionka H. Oxidative stress and starvation in Dinoroseobacter shibae: the role of extrachromosomal elements. Front Microbiol. 2015 Mar 25;6:233.
doi:10.3389/fmicb.2015.00233
PMID:25616803
Klingner A, Bartsch A, Dogs M, Wagner-Döbler I, Jahn D, Simon M, Brinkhoff T, Becker J, Wittmann C. Large-Scale 13C flux profiling reveals conservation of the Entner-Doudoroff pathway as a glycolytic strategy among marine bacteria that use glucose. Appl Environ Microbiol. 2015 Apr;81(7):2408-22.
doi:10.1128/AEM.03157-14
PMID:25452281
Szafranski SP, Wos-Oxley ML, Vilchez-Vargas R, Jáuregui R, Plumeier I, Klawonn F, Tomasch J, Meisinger C, Kühnisch J, Sztajer H, Pieper DH, Wagner-Döbler I. High-resolution taxonomic profiling of the subgingival microbiome for biomarker discovery and periodontitis diagnosis. Appl Environ Microbiol. 2015 Feb;81(3):1047-58.
doi: 10.1128/AEM.03534-14
PMID:25475081
Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Döbler I, Zeng AP. Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level. J Oral Microbiol. 2014 Dec 3;6:26189.
doi:10.3402/jom.v6.26189